Micro-line vial filling solution for biopharmaceuticals
Ensure batch consistency and sterility in fill-finish operations with a compact design capable of high-speed, aseptic filling of both liquids and powders, seamlessly integrating into your existing production line.

Fills, Stoppers, and Caps Vials Efficiently
The Hull i-Dositecno Micro-Line Vial Filling Systems from ATS Scientific Products address crucial challenges in biopharmaceutical production. These systems ensure precise and consistent filling, stoppering, and capping of vials, accommodating both liquid and powder products. Designed for applications such as vaccines, insulin, and diagnostic reagents, the systems support diverse end-product forms like eye drops and protein powders. With an output of up to 200 units per minute, the servo-driven motion-controlled design provides efficiency and accuracy, seamlessly integrating into your existing production line. Featuring compliance with cGMP and FDA standards, the Micro-Line equipment offers versatility with quick-change parts and aseptic filling systems to meet all production requirements. The systems are equipped with Siemens or Allen Bradley PLCs that facilitate easy automation and customization, ensuring optimal performance and minimal maintenance downtime.
Benefits
- Enhances production efficiency with high-speed filling, achieving up to 200 units per minute.
- Minimizes contamination risk through aseptic design and 100% non-destructive In-Process Weight Control.
- Offers flexibility with easy changeover for multiple vial formats and product types.
- Ensures compliance with cGMP, Annex 1, and FDA standards, meeting stringent regulatory requirements.
- Reduces operational costs with low maintenance needs and durable construction materials.
- Applications
- Oral solutions,Powder fill,Biopharmaceuticals,Test kits,Diagnostic,Veterinary health products,Human injectables,Ophthalmic eye care solutions
- End products
- Protein powders,Vaccines,Pregnancy test kits,Insulin,Vitamin powder supplements,Monoclonal antibodies,Veterinary antibiotics,Cough syrups,Eye drops,Veterinary vaccines,Oral suspensions,Artificial tears,Diagnostic reagents
- Steps before
- Vial Washing,Sterilization,Depyrogenation,Pre-Fill Inspection
- Steps after
- Freeze Drying,Capping,External Vial Washing,Packing
- Input ingredients
- liquid,powder,bulk vials,ready-to-use (RTU) vials
- Output ingredients
- filled vials,stoppered vials,capped vials
- Market info
- Filling speed
- 50 or 200 units per minute (upm)
- Filling volume
- 100µL to 500 mL
- Automation
- Servo-driven,PLC-controlled
- Compliance
- 21 CFR Part 11
- Batch consistency
- Guaranteed
- Container type
- Vials
- Materials
- Polyoxymethylene Copolymer (POMc)
- Filling nozzle options
- One or two nozzles
- Filling method
- Peristaltic pump / ceramic/SS rotary piston
- Cleanroom compatibility
- Cleanroom ready
- Control system
- Siemens or Allen Bradley PLC
- Changeover capability
- Quick changeover with POMc parts
- Filling type
- Liquid or powder
- Pick and place channels
- Up to 2-channel
- Filling speed
- 50 or 200 upm
- Automation level
- PLC-controlled servo motors
- Batch vs. continuous operation
- Batch
- Changeover time
- Quick changeover with POMc parts
- CIP/SIP
- Available
- GMP Compliance
- cGMP,Annex 1
- 21 CFR Part 11
- Integrated software
- IQ/OQ Validation Packages
- Available
- GAMP
- GAMP5
- Machine footprint
- Compact design
- Control panel type
- Siemens or Allen Bradley PLC-controlled
- No. of filling nozzles
- 1 or 2
- Discharge method
- Servo-driven star wheel transport
- Transport type
- Servo-driven star wheel
- Material for change parts
- Polyoxymethylene Copolymer (POMc)
- Control panel type
- Siemens or Allen Bradley PLC-controlled
- Compact footprint
- Yes
- Filling nozzle configuration
- One or two filling nozzles
- Feeding system type
- Tanks or bag holder inside machine
- Integration possibilities
- Compatible with vial washers,sterilization tunnels,freeze dryer systems,capping machines
- Changeover materials
- POMc (Polyoxymethylene Copolymer) or PEEK (Polyether ether ketone)
- Filling options
- Aseptic liquid dosing by peristaltic pump or ceramic/SS rotary piston,micro-dose,and solid powder filling by micro-auger
- Output rate configuration
- Automatically set via servo motors