Glass bioreactor for mammalian cell culture

Optimize your bioprocessing with advanced mixing and cooling capabilities, designed to enhance yield and efficiency in cell culture and fermentation processes.

Facilitates Efficient Cell Culture and Fermentation

The HyPerforma™ Glass Bioreactor from Thermo Scientific is designed to meet the demanding needs of biopharmaceutical and biotechnology processes. This bioreactor stands out with its computational fluid dynamics-optimized impellers, ensuring maximal mixing efficiency with minimal shear, thus preserving cell viability. Ideal for applications ranging from monoclonal antibody production to gene therapy vector development, it is engineered for precision in both pilot and bench-top operations.

Constructed with borosilicate glass and 316L stainless steel, this bioreactor offers superior chemical resistance and durability. The innovative bidirectional control system allows seamless transition between mammalian cell culture and fermentation processes. Its ergonomic design simplifies assembly and maintenance, while the novel cooling loop guarantees superior thermal performance, reducing cooling times by 50% compared to similar models. Suitable for both cGMP and research laboratory environments, the HyPerforma™ Glass Bioreactor integrates effortlessly into existing production lines, enabling scalable and reproducible outcomes.

Benefits

  • Enhances production efficiency with optimized mixing and minimal cell damage.
  • Improves thermal management, reducing cooling times by 50%.
  • Versatile for both mammalian culture and fermentation, expanding application range.
  • Ergonomically designed for swift assembly and maintenance, minimizing operational downtime.
  • Complies with cGMP standards, ensuring regulatory compliance in pharmaceutical production.

General


Applications
Cell culture,Biopharmaceuticals,Mammalian applications,Fermentation processes
End products
Biologic drugs,Gene therapy vectors,Cell-based assays,Monoclonal antibodies,Probiotic cultures,Insulin production,Recombinant proteins,Vaccine production
Steps before
Cell preparation,Media preparation,Suspension setup
Steps after
Harvesting,Filtration,Purification
Input ingredients
suspension cell culture,adherent cell culture,mammalian cell culture,fermentation processes
Output ingredients
cultured cells,biomanufactured products
Market info
Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.

Technical Specifications


Height
463.5 mm (18.3 in.)
Width
680 mm (26.8 in.)
Material
Borosilicate Glass,Stainless Steel (316L),Silicone
Weight
23.0 kg
Max. Voltage
240 V
KLa
Higher average due to impeller design
Cooling Rate
Two times better than a sample of products from other suppliers

Operating Characteristics


Working Mechanism
Impellers for maximum mixing with minimum shear
Automation level
Bidirectional control
Batch vs. continuous operation
Batch
Cleaning method
Manual
Energy efficiency
Improved cooling rate

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine Footprint
Height
Material
Borosilicate Glass,Stainless Steel (316L),Silicone
Weight
23.0 kg
Voltage
Max. 240 V

Custom Options


Control panel type
Bidirectional control
Cooling system
Cooling loop
Impeller type
CFD simulator designed
Motor adapter
Coupling windows and alignment marker
Vessel type
Single-wall vessel
Head plate design
Ergonomic