Glass bioreactor for mammalian cell culture
Optimize your bioprocessing with advanced mixing and cooling capabilities, designed to enhance yield and efficiency in cell culture and fermentation processes.

Facilitates Efficient Cell Culture and Fermentation
The HyPerforma™ Glass Bioreactor from Thermo Scientific is designed to meet the demanding needs of biopharmaceutical and biotechnology processes. This bioreactor stands out with its computational fluid dynamics-optimized impellers, ensuring maximal mixing efficiency with minimal shear, thus preserving cell viability. Ideal for applications ranging from monoclonal antibody production to gene therapy vector development, it is engineered for precision in both pilot and bench-top operations.
Constructed with borosilicate glass and 316L stainless steel, this bioreactor offers superior chemical resistance and durability. The innovative bidirectional control system allows seamless transition between mammalian cell culture and fermentation processes. Its ergonomic design simplifies assembly and maintenance, while the novel cooling loop guarantees superior thermal performance, reducing cooling times by 50% compared to similar models. Suitable for both cGMP and research laboratory environments, the HyPerforma™ Glass Bioreactor integrates effortlessly into existing production lines, enabling scalable and reproducible outcomes.
Benefits
- Enhances production efficiency with optimized mixing and minimal cell damage.
- Improves thermal management, reducing cooling times by 50%.
- Versatile for both mammalian culture and fermentation, expanding application range.
- Ergonomically designed for swift assembly and maintenance, minimizing operational downtime.
- Complies with cGMP standards, ensuring regulatory compliance in pharmaceutical production.
- Applications
- Cell culture,Biopharmaceuticals,Mammalian applications,Fermentation processes
- End products
- Biologic drugs,Gene therapy vectors,Cell-based assays,Monoclonal antibodies,Probiotic cultures,Insulin production,Recombinant proteins,Vaccine production
- Steps before
- Cell preparation,Media preparation,Suspension setup
- Steps after
- Harvesting,Filtration,Purification
- Input ingredients
- suspension cell culture,adherent cell culture,mammalian cell culture,fermentation processes
- Output ingredients
- cultured cells,biomanufactured products
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Height
- 463.5 mm (18.3 in.)
- Width
- 680 mm (26.8 in.)
- Material
- Borosilicate Glass,Stainless Steel (316L),Silicone
- Weight
- 23.0 kg
- Max. Voltage
- 240 V
- KLa
- Higher average due to impeller design
- Cooling Rate
- Two times better than a sample of products from other suppliers
- Working Mechanism
- Impellers for maximum mixing with minimum shear
- Automation level
- Bidirectional control
- Batch vs. continuous operation
- Batch
- Cleaning method
- Manual
- Energy efficiency
- Improved cooling rate
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine Footprint
- Height
- Material
- Borosilicate Glass,Stainless Steel (316L),Silicone
- Weight
- 23.0 kg
- Voltage
- Max. 240 V
- Control panel type
- Bidirectional control
- Cooling system
- Cooling loop
- Impeller type
- CFD simulator designed
- Motor adapter
- Coupling windows and alignment marker
- Vessel type
- Single-wall vessel
- Head plate design
- Ergonomic