Scalable bioprocess control system
Optimize your bioprocesses with a configurable control system that ensures seamless data transfer and reduced development times, essential for maintaining efficiency and quality from research to full-scale production.
Automates and Integrates Bioreactor Processes
The Applikon V-Control from Getinge Applikon integrates seamlessly into biopharmaceutical and biotechnology environments, offering a comprehensive automation solution for bioreactor processes. This system uniquely combines Applikon’s bioreactor expertise with Emerson’s DeltaV automation, facilitating process control, automation, and data acquisition across all scales—from R&D through to full-scale production.
Specially designed to optimize processes such as batch, fed-batch, and continuous cultivation, it supports the production of monoclonal antibodies, vaccines, and other biologics. Utilizing open architecture, V-Control enables customizable integration with existing DeltaV platforms, ensuring seamless technology transfer and scalable data management.
Equipped for both single-use and multi-use operations, V-Control supports customized configurations to match specific process needs, including multiple gas flows and integration with third-party sensors. The system reduces development time and cost by utilizing pre-configured modules and enabling easy upscaling.
Engineered to meet stringent industry standards, it supports GMP and FDA compliance, with automation capabilities that enhance operator efficiency. The system is compatible with clean-in-place (CIP) processes, making maintenance straightforward. Furthermore, V-Control offers engineering support for tailored solutions to meet unique operational requirements, ensuring it meets the rigorous demands of pharmaceutical manufacturers and biotechnology firms.
Benefits
- Streamlines technology transfer and reduces time-to-market with seamless integration across development phases.
- Minimizes operational errors and training needs through a user-friendly interface and centralized control.
- Enhances process efficiency and product quality with precise bioprocess monitoring and automation.
- Customizable configurations support diverse applications, ensuring flexibility and scalability in production.
- Ensures compliance with industry standards, supporting regulatory approvals and market entry.
- Applications
- Cell culture,Continuous cultivation,Microbial cultivation,Biopharmaceuticals,Batch processes,Fed-batch processes,Perfusion processes
- End products
- Biologics,Vaccines,Insulin,Monoclonal antibodies,Viral vectors for gene therapy,Hemoglobin solutions,Enzymes,Biopharmaceutical intermediates,Therapeutic proteins,Probiotics
- Steps before
- Bioreactor setup,Media preparation,Inoculum culture preparation
- Steps after
- Data analysis,Technology transfer,Product purification
- Input ingredients
- bioreactor systems,DeltaV libraries,bioprocessing data,technology for bioprocess optimization,third-party sensors,control systems data,Applikon control units,Emerson DeltaV automation tools
- Output ingredients
- optimized bioprocesses,automated process control,data acquisition,visualization,reduced development lead times,seamless technology transfer,configured bioreactor systems,integrated bioprocess solutions
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.
- Automation
- DeltaV automation,PLC-controlled
- Capacity
- 250 mL to 20 L for R,D,customizable for pilot,production
- Batch vs. continuous
- Batch
- Communication Protocol
- OPC
- Control System
- DeltaV PK Controller
- Gas Flow Control
- 3 mass flow controllers for air,O2,and CO2
- Heating
- Heating blanket
- Measurement Sensors
- pH,DO,temperature
- System Compatibility
- Stainless steel,single-use systems
- Software Platform
- DeltaV Discovery
- Integration Capability
- 3rd party sensors,external historians like OSIsoft PI
- Scalability
- Up to 32 bioreactor units per network
- Configuration
- Customizable packages,pre-configured bundles
- Automation level
- DeltaV / PLC
- Batch vs. continuous operation
- Batch / Fed-Batch / Continuous
- Data acquisition
- Integrated DeltaV system
- Technology transfer
- Seamless from R,D to Pilot,Production
- User interface design
- Emerson’s Human-Centered Design
- Integration capability
- With third-party sensors and systems
- System Control
- V-Control integrated with DeltaV
- Operation mode
- Manual / Automated
- Scale-up capability
- Optimized for Discovery to Production
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Bioreactor size
- 250 mL to 20 L
- Control system size
- Compact DeltaV ProfessionalPlus PC
- Gas flow control
- Multiple gas flows,3 mass flow controllers for air,O2,and CO2
- Heating equipment
- Heating blanket
- Stirring mechanism
- Stirrer motor
- Tank construction
- Stainless steel or single-use systems
- Control panel type
- DeltaV ProfessionalPlus PC
- Integration possibilities
- OPC communication and integration with DeltaV systems
- Bioreactor configuration
- Single-use or multi-use
- Gas flow customization
- Multiple gas flows
- Sensor integration
- Integration with 3rd party sensors
- Expansion packs
- V-Control Batch and DeltaV Configuration Management