Low shear mixer for shear-sensitive applications

Optimize shear-sensitive mixing with precision control, enhancing product integrity by minimizing mechanical stress and wear—ideal for delicate bio-molecules and chemical compositions.

Mixes and Emulsifies Shear-Sensitive Biopharmaceuticals

The Truelev Mixer from Metenova offers a revolutionary solution for shear-sensitive biopharmaceutical applications. Utilizing fully levitating, bearing-less technology, the Truelev Mixer provides gentle mixing without mechanical friction, tailored for sensitive tasks such as proteins and enzyme solutions. This mixer is ideal for producing high-value biopharmaceutical products, including monoclonal antibodies and vaccine formulations. It integrates seamlessly into both batch and continuous operations within pharmaceutical and biotech industries.

Engineered with electromagnetic bearings, the Truelev Mixer eliminates wear parts, achieving maintenance-free operation and reducing risk of contamination or product compromise. It collects real-time performance data for superior process control and analytics. Available configurations include the Truelev Mobile, designed for mobile vessels required between multiple facilities. This system is constructed from high-grade materials ensuring chemical compatibility, and it adheres to GMP and FDA standards, providing assurance in regulatory compliance for pharmaceutical manufacturing.

Configurability includes optional Mix Heads for diverse process needs, and comprehensive customization support is offered to adapt to specific production requirements. This sophisticated mixer ensures efficient, contamination-free cleaning, thanks to its integrated cleaning capabilities, aligning with strict industry hygiene standards.

Benefits

  • Minimizes risk of product damage and contamination with maintenance-free, bearing-less design.
  • Enhances process control and efficiency with real-time performance data collection.
  • Complies with GMP and FDA standards for pharmaceutical and biopharmaceutical applications.
  • Offers flexibility with mobile vessel configuration for multi-facility operations.
  • Provides reliable chemical compatibility with high-grade, corrosion-resistant materials.

General


Applications
Biopharmaceuticals,Proteins,Fine chemicals,Shear-sensitive products
End products
Monoclonal antibodies,Insulin solutions,Enzyme solutions,Vaccine formulations,Recombinant protein therapies,Lipid nanoparticle suspensions,Plasmid dna preparations
Steps before
Purification,Preparation of mobile vessels,Mix Head installation
Steps after
Cleaning,Sterilization (CIP/SIP),Data collection,Mixer control analysis
Input ingredients
Output ingredients
Market info
Mete Nova is known for its expertise in manufacturing customized engineered-to-order (ETO) industrial equipment, acclaimed for its precision engineering, reliability, and tailored solutions to meet specific client needs across various industrial sectors.

Technical Specifications


Automation
Real-time performance data collection
Maintenance
Maintenance-free (no wear parts)
Cleaning method
CIP/SIP compatibility
Mixing technology
Fully levitating,bearing-less
Mixing type
Low shear mixing
Compatibility
Mobile vessel use
Control capability
Superior mixing control
Magnetic bearing
Active electromagnetic

Operating Characteristics


Working Mechanism
Bearing-less,fully levitating Mix Head
Automation level
Real-time performance data collection
Cleaning method
Maintenance-free,no wear parts
Shear sensitivity
Low shear mixing for sensitive applications

Material Compatibility


Cleanability
CIP/SIP

Physical Characteristics


Mixing Technology
Levitating,bearing-less
Drive Unit
Removable for mobile vessels
Mix Head
Fully levitating,electromagnetic bearing
Container Type
Mobile vessels
Material Compatibility
Corrosion-resistant materials
Tank Plate
Customizable,DS-039,DS-040
Control Panel Type
Controller,DS-042
Compact Footprint
Yes

Custom Options


Integration Possibilities
Process analytics and mixer control
Maintenance-Free
Yes,no wear parts