Continuous granulation and drying system for r&d
Develop precise pharmaceutical granules with this compact system, tailored for small-scale continuous granulation and drying, ensuring consistent quality and seamless scalability from research to production without the need for extensive scale-up.

Processes Continuous Granulation and Drying
The ConsiGma® GD 25/80 from GEA is a continuous twin-screw granulator and dryer, designed for pharmaceutical R&D. It allows precise control over granule quality across small-scale production, seamlessly integrating into your workflow to develop continuous granulation processes. Using a single-stage continuous operation, it facilitates granulation and drying, streamlining the production of pharmaceutical granules, coated, controlled-release, hygroscopic, and friable tablets. With a starting capacity from just a few hundred grams, it ensures efficient use of active pharmaceutical ingredients, reducing material waste. The system’s twin-screw granulator is complemented by a compact dryer, enabling full integration into small-scale R&D operations without additional space requirements. The equipment is designed for flexibility, offering options like Brabender or Ktron feeders and solvent compatibility, ensuring adaptability to various formulations and process conditions. Its compact footprint and fast R&D capabilities reduce time to market and ensure rapid process development, with no need for scale-up between the GD 25/80 to GD or GC lines. Designed to comply with industry standards, it provides a valuable solution for pharmaceutical manufacturers seeking to optimize early-stage drug development.
Benefits
- Minimizes raw material usage, enhancing cost-efficiency during R&D.
- Eliminates scale-up challenges, ensuring smooth transition to full-scale production.
- Accelerates process development, reducing time-to-market for new pharmaceuticals.
- Integrates seamlessly into existing R&D setups, optimizing space and resources.
- Facilitates precise quality control of small batches, improving product consistency.
- Applications
- Continuous granulation processes,Coating materials,Pharmaceutical tablets,Pharmaceuticals
- End products
- Coated tablets,Friable tablets,Hygroscopic tablets,Melt granulated products,Controlled-release tablets,Pharmaceutical granules
- Steps before
- Powder Blending,Liquid Addition
- Steps after
- Drying,Tablet Coating,Compression,LOD Measurement
- Input ingredients
- powder,liquid,API,solvent
- Output ingredients
- granules,dry granules,high-quality granules
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Granulation Technology
- Continuous twin-screw
- Dryer Type
- Standalone
- Granulator Type
- Twin-screw
- Batch/Continuous Operation
- Continuous
- R,D Scale
- Small-scale
- Product Quantity Capacity
- A few 100 grams to a few kilograms
- Powder Feeder
- 1 unit
- Liquid Addition System
- 1 unit
- Dryer Segment
- 1 unit
- Automation
- Not specified
- Material Compatibility
- Solvent compatible option available
- Working mechanism
- Twin-screw granulation
- Integrated steps
- Granulation and Drying
- Batch vs. continuous operation
- Inline Continuous
- Automation level
- PLC
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Cleaning method
- CIP / Manual
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Twin-screw granulator size
- Small-scale
- Discharge method
- Continuous
- Powder feeder
- Standalone
- Dryer segment size
- Small-scale
- Unit size
- GD 25/80
- Standalone or Integrated System
- Standalone GD 25 with/without dryer segment
- Feeder Type
- Brabender or Ktron Feeder
- Solvent Compatibility
- Yes
- Second Liquid Addition
- Available
- Lighthouse Probe® for LOD Measurement
- Available
- Melt Granulation Set-up
- Available