Centrifugal Partition Chromatography System for Purification and Separation
Traditional chromatography methods for natural compounds, pharmaceuticals, or specialty chemicals can result in sample loss or require expensive stationary phases. With centrifugal partition chromatography (CPC), you can perform high-resolution separations using only liquid-liquid partitioning, minimizing waste while maintaining maximum product recovery.
High-Purity Fractionation Without Solid Stationary Phases
The FCPC® system from Rousselet Kromaton is a high-performance centrifugal partition chromatograph (CPC) designed for continuous liquid-liquid separation of complex mixtures. Unlike chromatography techniques that rely on solid-phase media, CPC uses a liquid stationary phase, retained in the system’s rotating cells by centrifugal force. This allows for high-yield, solvent-efficient purification, reducing both material costs and environmental impact.
With scalable configurations from laboratory to industrial production, FCPC® systems are widely used in pharmaceuticals, botanicals, fine chemicals, and food processing. The system operates across a wide range of polarities, making it ideal for fractionating alkaloids, flavonoids, lipids, proteins, and other bioactive molecules.
Key advantages include solvent recycling capability, fast method development, and minimal sample loss, making it a superior alternative to traditional preparative HPLC. The modular design enables seamless integration into existing purification workflows, providing a scalable, cost-effective solution for high-purity compound isolation.
Benefits
- Lower costs, no risk of sample loss from adsorption
- Continuous liquid-liquid chromatography
- Reduces solvent consumption and waste
- Scalable from lab to production
- Adjustable flow rates and retention parameters