Hot cell system for solid target manipulation in radiopharma

Optimize radiopharmaceutical synthesis with precise manipulation and seamless integration, ensuring reliable handling and packaging of Tl-201 and Ga-67.

Manipulates and Synthesizes Radiopharmaceuticals

The SPECT Production Hot Cell from Comecer is a comprehensive solution for the manipulation and synthesis of radiopharmaceuticals, such as Tl-201 and Ga-67. Comprising seven interconnected hot cells, this system integrates master-slave manipulators and automatic dispensing with shielded transport pots. Each stage—receiving, recovering, synthesizing, dispensing, and transferring—utilizes robust materials, like PVC and lead shielding of 75 to 150 mm, ensuring safety during handling of irradiated materials. The PLC-controlled conveyor facilitates seamless operation among cells, while robotic arms conduct precise dispensing. Built to align with current GMP guidelines, it supports both manual and automated operations, making it ideal for radiopharmaceutical manufacturers and nuclear medicine facilities seeking efficient, compliant production of solid radiopharmaceuticals.

Benefits

  • Enhances safety and precision with lead-shielded chambers and robotic dispensing.
  • Facilitates seamless integration and operation across production lines with automated transfers.
  • Complies with GMP standards, ensuring regulatory adherence for pharmaceutical manufacturing.
  • Increases efficiency by combining manual and automated operations for streamlined processing.
  • Minimizes contamination risk through dedicated cells for specific materials and processes.

General


Applications
Nuclear medicine therapy,Radiopharmaceuticals
End products
Ga-67 radiopharmaceutical,Tl-201 radiopharmaceutical
Steps before
Irradiation,Receiving irradiated targets
Steps after
Dispensing,Calibration,Packaging,Transportation
Input ingredients
irradiated materials,solid targets,Tl-201,Ga-67
Output ingredients
radiopharmaceutical,shielded transport pots,packaged radiopharmaceuticals
Market info
Comecer is known for manufacturing advanced containment and isolation systems, particularly in the pharmaceutical and nuclear medicine sectors, with expertise in custom-engineered equipment, ensuring high safety and compliance standards.

Technical Specifications


Shielding Thickness
75–150 mm of lead
Working Chamber Material
PVC
Number of Hot Cells
Seven
Radio-Fluids Inlet Lines
Yes
Transfer System
Conveyor
Robotic Arm
Automatic Dispensing
Main Isotopes Handled
Tl-201,Ga-67

Operating Characteristics


Manipulation method
Master-slave manipulators
Automation level
Robotic arm for dispensing
Transfer system
Conveyor
Shielding thickness
75 to 150 mm of lead
Material Compatibility
PVC for working chambers
Product synthesis
Chemistry Hot Cells
Dispensing Technique
Automatic Dispensing Systems
Packaging method
Shielded transport pots
Product handling
Radio-fluids inlet lines
Material transfer
Lower tunnel with tray

Material Compatibility


Corrosive resistance (e.g. acids)
Yes

Physical Characteristics


Footprint
Multiple hot cells
Shielding Material
Lead
Shielding Thickness
75–150 mm
Material
PVC (working chambers)
Transfer System
Conveyor
Discharge Method
Radio-fluids inlet lines
Automation Level
Robotic arm for dispensing

Custom Options


Control panel type
HMI / Touchscreen
Integration possibilities
Robotic arm,Radio-fluids inlet lines
Shielding options
75 to 150 mm of lead
Working chamber material
PVC
Hot cell configuration
Seven cells with transfer system