Single-use bioreactors for microbial fermentation
Optimize high-density fermentation with advanced single-use bioreactor technology, ensuring efficient mixing and mass transfer for robust microbial applications while minimizing contamination risks.
Facilitates Scalable Microbial Fermentation Processes
The BioBLU®f Single-Use Bioreactors from Eppendorf are specially designed for microbial applications, offering a rigid-walled stirred-tank format ideal for high-cell density fermentation. These bioreactors mimic traditional designs, ensuring effective mixing and mass transfer. They are suitable for producing monoclonal antibodies, insulin, and biofuels, with a working volume range of 65 mL to 3.75 L. Optimized for processes such as fermentation and cultivation, they integrate seamlessly with Eppendorf’s bioprocess controllers and selected third-party systems. With fully enclosed bearings and a sealed magnetic drive, they maintain sterility, while interior baffles and Rushton-type impellers ensure efficient mixing. Available in presterilized, autoclavable configurations, they support high agitation speeds and effective cooling, addressing the complex needs of the pharmaceutical, biotech, and biofuel industries while minimizing process risks.
Benefits
- Enhances fermentation efficiency for high-cell density cultures, increasing yield.
- Streamlines scalability from lab to production with flexible volume options.
- Maintains vessel sterility to minimize contamination risks.
- Compatible with existing bioprocess systems for seamless integration.
- Reduces operational downtime with presterilized, ready-to-use configurations.
- Applications
- Liquid formulations,Fine chemicals,Nutraceuticals,Biopharmaceuticals,Enzymes,Biofuel
- End products
- Cellulase,Amino acids,Vitamins,Vaccines,Insulin,Suspension concentrates,Monoclonal antibodies,Emulsions,Ethanol-based fuels,Lactase,Biodiesel,Dietary supplements
- Steps before
- Preparation of culture media,Inoculum development,Sterilization of input materials
- Steps after
- Fermentation monitoring,Harvesting,Downstream processing
- Input ingredients
- bacteria,yeasts,fungi,nutrient media,oxygen,temperature control agents
- Output ingredients
- fermentation products,proteins,plasmids,cultivated microorganisms
- Market info
- Eppendorf is known for manufacturing high-quality laboratory equipment, including pipettes, centrifuges, and bioprocessing tools. Renowned for their precision and reliability, Eppendorf's products are widely used in scientific research and clinical laboratories worldwide.
- Bioreactor Type
- Single-Use,Stirred-Tank
- Wall Type
- Rigid
- Working Volume
- 65 mL–3.75 L
- Fermentation Application
- Bacteria,Yeasts,Fungi
- Mixing
- Rushton-type Impellers
- Sterilization
- β-ray or X-ray Irradiated
- Scalability
- Yes,compatible with bench-scale bioprocess controllers
- Cooling Option
- Cooling Baffles or Fingers
- Exhaust Treatment
- Liquid-free Exhaust Condensation
- Impeller Type
- Multiple Rushton-type
- Mass Transfer Efficiency
- High
- Temperature Control
- Baffles for Heat Removal
- Automation
- Manual / Compatible with Bioprocess Controllers
- Sensors
- pH,DO,Temperature
- Cooling Medium
- Electric Heater Band or Water-Cooled
- Materials
- Headplate Ports,Sparger,Gas Filters
- Drive Type
- Sealed Magnetic Drive
- Working mechanism
- Stirred-tank design
- Automation level
- Manual / PLC
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP 121°C / SIP available
- Cleaning method
- Presterilized / Autoclavable
- Exhaust treatment
- Liquid-free exhaust condensation (Peltier),electric heater band,water-cooled
- Impeller type
- Multiple Rushton-type
- Cooling options
- Cooling baffles or cooling fingers
- Biological compatibility
- Yes
- Microbial application
- Bacteria,yeasts,fungi
- Sterility Assurance Level (SAL)
- 10^-6
- Tank shape
- Stirred-tank
- Working volume range
- 65 mL – 3.75 L
- Impellers
- Multiple Rushton-type
- Sterilization method
- β-ray or X-ray
- Autoclavable
- Wall type
- Rigid-walled
- Baffles
- Interior baffles
- Cooling option
- Cooling baffles or cooling fingers
- Integration possibilities
- Compatible with Eppendorf and selected third-party controllers
- Port customization
- Spare Pg 13.5 ports for single-use septa,tri-ports,compression fitting adaptors