Single-use bioreactors for microbial fermentation

Optimize high-density fermentation with advanced single-use bioreactor technology, ensuring efficient mixing and mass transfer for robust microbial applications while minimizing contamination risks.

Facilitates Scalable Microbial Fermentation Processes

The BioBLU®f Single-Use Bioreactors from Eppendorf are specially designed for microbial applications, offering a rigid-walled stirred-tank format ideal for high-cell density fermentation. These bioreactors mimic traditional designs, ensuring effective mixing and mass transfer. They are suitable for producing monoclonal antibodies, insulin, and biofuels, with a working volume range of 65 mL to 3.75 L. Optimized for processes such as fermentation and cultivation, they integrate seamlessly with Eppendorf’s bioprocess controllers and selected third-party systems. With fully enclosed bearings and a sealed magnetic drive, they maintain sterility, while interior baffles and Rushton-type impellers ensure efficient mixing. Available in presterilized, autoclavable configurations, they support high agitation speeds and effective cooling, addressing the complex needs of the pharmaceutical, biotech, and biofuel industries while minimizing process risks.

Benefits

  • Enhances fermentation efficiency for high-cell density cultures, increasing yield.
  • Streamlines scalability from lab to production with flexible volume options.
  • Maintains vessel sterility to minimize contamination risks.
  • Compatible with existing bioprocess systems for seamless integration.
  • Reduces operational downtime with presterilized, ready-to-use configurations.

General


Applications
Liquid formulations,Fine chemicals,Nutraceuticals,Biopharmaceuticals,Enzymes,Biofuel
End products
Cellulase,Amino acids,Vitamins,Vaccines,Insulin,Suspension concentrates,Monoclonal antibodies,Emulsions,Ethanol-based fuels,Lactase,Biodiesel,Dietary supplements
Steps before
Preparation of culture media,Inoculum development,Sterilization of input materials
Steps after
Fermentation monitoring,Harvesting,Downstream processing
Input ingredients
bacteria,yeasts,fungi,nutrient media,oxygen,temperature control agents
Output ingredients
fermentation products,proteins,plasmids,cultivated microorganisms
Market info
Eppendorf is known for manufacturing high-quality laboratory equipment, including pipettes, centrifuges, and bioprocessing tools. Renowned for their precision and reliability, Eppendorf's products are widely used in scientific research and clinical laboratories worldwide.

Technical Specifications


Bioreactor Type
Single-Use,Stirred-Tank
Wall Type
Rigid
Working Volume
65 mL–3.75 L
Fermentation Application
Bacteria,Yeasts,Fungi
Mixing
Rushton-type Impellers
Sterilization
β-ray or X-ray Irradiated
Scalability
Yes,compatible with bench-scale bioprocess controllers
Cooling Option
Cooling Baffles or Fingers
Exhaust Treatment
Liquid-free Exhaust Condensation
Impeller Type
Multiple Rushton-type
Mass Transfer Efficiency
High
Temperature Control
Baffles for Heat Removal
Automation
Manual / Compatible with Bioprocess Controllers
Sensors
pH,DO,Temperature
Cooling Medium
Electric Heater Band or Water-Cooled
Materials
Headplate Ports,Sparger,Gas Filters
Drive Type
Sealed Magnetic Drive

Operating Characteristics


Working mechanism
Stirred-tank design
Automation level
Manual / PLC
Batch vs. continuous operation
Batch
CIP/SIP
CIP 121°C / SIP available
Cleaning method
Presterilized / Autoclavable
Exhaust treatment
Liquid-free exhaust condensation (Peltier),electric heater band,water-cooled
Impeller type
Multiple Rushton-type
Cooling options
Cooling baffles or cooling fingers

Material Compatibility


Biological compatibility
Yes

Product type Characteristics


Microbial application
Bacteria,yeasts,fungi


Sterility Assurance Level (SAL)
10^-6

Physical Characteristics


Tank shape
Stirred-tank
Working volume range
65 mL – 3.75 L
Impellers
Multiple Rushton-type
Sterilization method
β-ray or X-ray
Autoclavable
Wall type
Rigid-walled
Baffles
Interior baffles
Cooling option
Cooling baffles or cooling fingers

Custom Options


Integration possibilities
Compatible with Eppendorf and selected third-party controllers
Port customization
Spare Pg 13.5 ports for single-use septa,tri-ports,compression fitting adaptors