Multi-parallel bioreactors for cell line selection and process development
Enhance your biopharmaceutical production with scalable multi-parallel bioreactors, enabling rapid cell line selection and process optimization, while minimizing time and resources in your development workflow.

Facilitates Clone Screening and Process Optimization
The Ambr® series from Sartorius offers state-of-the-art multi-parallel bioreactor systems like the Ambr® 15 Cell Culture and Ambr® 250 variants, which are engineered to enhance biopharmaceutical production processes. These systems excel in rapid clone screening and process optimization through automated liquid handling and data integration, making them invaluable for biopharmaceutical, cell and gene therapy, and monoclonal antibody production. Designed to handle small-scale, high-throughput operations effectively, these bioreactors support a range of cell cultures, including mammalian and microbial, with customizable vessel configurations. The single-use design optimizes cleaning and maintenance, while built-in data analytics tools facilitate process scaling and integration into existing production workflows. Compliant with industry standards, these systems are suitable for environments demanding stringent process control and efficiency.
Benefits
- Enhances process efficiency by allowing simultaneous evaluation of multiple cell lines or clones.
- Reduces setup and turnaround times with single-use, pre-assembled bioreactor vessels.
- Improves scalability potential with integrated data analytics tools for seamless process transfer.
- Lowers operational costs through automated sampling and data management.
- Ensures compliance with biopharmaceutical production standards for reliable process control.
- Applications
- Biologics,Vaccines,Monoclonal antibodies,Biosimilars,Regenerative medicine,Biopharmaceuticals,Cell and gene therapy
- End products
- Biontech bnt162 vaccine,Moderna mrna-1273 vaccine,Bluebird bio car-t cell therapy,Novartis kymriah®,Crispr therapeutic gene-edited therapies,Shanghai fosun pharmaceutical biosimilars,Regeneron pharmaceuticals monoclonal antibodies
- Steps before
- Clone selection,Media preparation,Inoculation,Calibration,Initial setup
- Steps after
- Process optimization,Data analysis,Scale-up,Quality control,Sampling
- Input ingredients
- cell lines,clones,microbial strains,media,feeds,inoculation densities,cell culture media composition
- Output ingredients
- process data,pH measurement,cell viability,viable cell density,metabolite levels,spectroscopic analysis results,product titer,glycosylation levels,critical quality attribute (CQA) information
- Market info
- Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.
- Vessel working volume
- 10 – 15 mL
- Vessel working volume
- 100 – 250 mL
- No. of parallel cultivations
- 24 – 48
- No. of parallel cultivations
- 2 – 8
- No. of parallel cultivations
- 12 – 24
- No. of parallel cultivations
- 12 – 24
- Cell culture types
- Insect and mammalian
- Culture type
- Microbial
- Automation
- Automated liquid handling
- Baffled vessel versions
- Available for mammalian and microbial cultures
- Unbaffled vessel versions
- Available for cell and gene therapy
- Operation space
- 2m of bench space
- Filtration method
- Integrated filtration with irradiated and pre-assembled consumables
- Analyzers compatibility
- Bioprocess analyzer technologies
- Measurement parameters
- pH,cell viability,viable cell density,metabolite levels,spectroscopic analysis
- Sample data transfer
- Automated transfer of bioreactor sample data
- Data management
- Simplified workflow reduces errors
- Perfusion process
- Scalable perfusion processes
- Software integration
- MODDE® Design of Experiments
- Automation level
- Manual / PLC / SCADA
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Batch vs. continuous operation
- Batch / Inline Continuous
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- 2m of bench space for 8 bioreactors
- Vessel working volume
- 10–15 mL,100–250 mL
- No. of parallel cultivations
- 24 – 48,2 – 8,12 – 24
- Vessel configuration
- Baffled for mammalian and microbial,unbaffled for cell and gene therapy
- Single-use bioreactors
- Yes
- Automation
- High-throughput automated operation
- Control panel type
- Touchscreen / HMI
- Integration possibilities
- PLC / SCADA Integration
- Automation options
- Manual / Semi-automatic / Fully automatic
- Scalability
- 10–250 mL mini bioreactors
- Vessel configuration
- Baffled / Unbaffled
- Number of parallel cultivations
- 2–48
- Liquid handling automation
- High-throughput automated
- Software integration
- MODDE® / Umetrics®
- Data connectivity
- Integrated analyzers / Data-connected analyzers