Multi-parallel bioreactors for cell line selection and process development
When developing biopharmaceuticals, selecting optimal cell lines and optimizing bioprocesses efficiently is crucial. Extensive comparative studies on cell lines, pH levels, temperature, and media compositions need to be conducted swiftly to meet production goals.
Automate parallel bioprocessing experiments
The Ambr® series from Sartorius is a suite of multi-parallel bioreactor systems designed for scalable and efficient cell culture process development. These systems allow for the simultaneous operation of multiple small-scale bioreactors, providing extensive process data in less time. Available models, including Ambr® 15 Cell Culture, Ambr® 250 Modular, Ambr® 250 High Throughput, and Ambr® 250 High Throughput Perfusion, offer capacities ranging from 10 mL to 250 mL. The single-use bioreactors simplify setup and accelerate turnaround, facilitating high-throughput automation for screening different clones, media, and feeds. The systems are integrated with automated liquid handling and data connectivity, enabling consistent and reproducible results for mammalian and microbial cultures. The process data can be easily scaled up to larger bioreactor systems such as the 2L Univessel® SU and Biostat STR®.
Benefits
- Simultaneously run multiple experiments for faster data collection
- Scalable from small-scale bioreactors to large production systems
- Automated setup and operation reduce manual intervention
- Single-use bioreactors minimize contamination risks
- Integrated data analytics enhance process understanding