Lab-scale in-situ sterilizable bioreactor
In R&D and university laboratories, precise control over fermentation and bioprocessing is crucial. Researchers often face challenges such as ensuring uniform conditions and scalability from benchtop to pilot scale, all while maintaining a sterile environment.
Facilitates scalable fermentations with in-situ sterilization
The KLF Bioreactor, manufactured by Bioengineering AG, offers a unique, in-situ sterilizable bench-top bioreactor made of glass. This bioreactor is distinguished by its ease of operation, requiring no tools for conversion and offering substantial flexibility with numerous extension possibilities. The system is optimized for batch, fed-batch, or perfusion processes and is equipped with accurate process control via high-grade probes. The KLF employs BioSCADA, a sophisticated control and visualization software, ensuring data collection and compliance with 21 CFR Part 11. The design allows for minimal space requirements and can support up to six bioreactors controlled by a single unit, making it ideal for both scale-up and scale-down testing. Technical features include multiple configurations for processing capacities (1.6, 2.0, and 2.5 liters), robust components, and compatibility with various stirring, ventilation, and measurement systems. The system’s versatility and reliable construction make it well-suited for biopharma, food, beverage, and cosmetic industries.
Benefits
- Supports various fermentation processes including batch, fed-batch, and perfusion
- Accurate process control with high-grade probes and BioSCADA software
- Minimal space requirements due to compact design
- Easy conversion and operation without the need for tools
- Scalable configuration, supporting up to six bioreactors with a single control unit