Hydrogenation reactors for safe and efficient syntheses

Experience safe, on-demand hydrogen generation for precise flow hydrogenation, reducing hazards traditionally associated with handling pressurized gases and pyrophoric materials—perfect for laboratories seeking to enhance synthetic reaction efficiency and safety.

Generates On-Demand Hydrogen for Catalytic Reactions

The H-Cube® Mini Plus from ThalesNano offers a unique solution for laboratory-scale continuous flow hydrogenation. This compact system generates hydrogen on-demand through water electrolysis, eliminating the need for stored gas cylinders. It supports a range of catalytic reactions crucial in pharmaceuticals, fine chemicals, and agrochemicals, such as the production of antihypertensive drugs and active pharmaceutical ingredients. With its ability to operate from atmospheric pressure to 100 bar and temperatures up to 100°C, the H-Cube® Mini Plus ensures precise control over reaction conditions. The system’s automation features include an integrated video tutorial, making it user-friendly for research and development departments. Adaptable across liquid, gas, and solid product types, it maintains energy efficiency with its controlled operation. The use of CatCart® cartridges simplifies catalyst handling and enhances safety. Configurable for various scales, it is optimal for both experimental and small-scale production needs.

Benefits

  • Enhances safety by eliminating the need for hydrogen gas cylinders.
  • Facilitates rapid reaction adjustments, optimizing lab throughput.
  • Supports diverse reactions, expanding research capabilities.
  • User-friendly interface reduces training time and errors.
  • Compact design conserves valuable laboratory space.

General


Applications
Fine chemicals,Fragrances,Agrochemicals,Academia,Flavors,Pharmaceuticals
End products
Cholesterol-lowering agents,Fragrance concentrates,Active pharmaceutical ingredients (apis),Research compounds,Antihypertensive drugs,Pesticide precursors,Food flavor enhancers,Insecticide intermediates,Essential oils
Steps before
Solvent Preparation,Reactant Solution Preparation,System Parameter Setting
Steps after
Product Collection,Post-Reaction Analysis
Input ingredients
water,pure solvent,reactants,hydrogen gas,catalyst cartridges (CatCarts®)
Output ingredients
reaction product,collection vial
Market info
Thalesnano is known for manufacturing advanced flow chemistry solutions, particularly in catalyst and hydrogenation technologies. They are recognized for their expertise in continuous processes, enhancing safety and efficiency in chemical synthesis.

Technical Specifications


Temperature range
From room temperature to 100°C
Pressure range
From atmospheric pressure to 100 bar
Flow rate
0.3 – 3 mL/min
Maximum hydrogen production rate
25-30 NmL/min
Water reservoir capacity
100 mL
Water specifications
Deionized water with maximum conductivity of 71 nS/cm (min. resistance 14 MΩcm)
Dimensions
Width
Weight
7.3 kg
Voltage
100 – 240 V AC
Typical catalyst amount
0.1 – 0.3 g
Recommended concentration
0.01 – 1 M

Operating Characteristics


Working mechanism
Hydrogen generation via electrolysis
Temperature range
Room temperature to 100°C
Pressure range
From atmospheric pressure to 100 bar
Hydrogen production rate
25-30 NmL/min
Flow rate
0.3 – 3 mL/min
Batch vs. continuous operation
Continuous
Automation level
Automated hydrogen drying system
Reaction scale
Milligrams to grams
CIP/SIP
Not specified

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Compact footprint
Width
Weight
7.3 kg (16.09 lb)
Discharge method
Packed column with catalyst stays behind
Control panel type
Built-in video tutorial

Custom Options


Control panel type
Built-in video tutorial
Integration possibilities
Hydrogen mode ON/OFF for different reaction types
Reaction scale variability
Milligrams to grams