Containment solutions for pharmaceutical production

Enhance operator safety and product integrity with advanced containment solutions, ensuring precise handling of sensitive materials during granulation and mixing processes in pharmaceutical production.

Granulates and Mixes Pharmaceutical Compounds

The containment mixer granulator from DIOSNA seamlessly integrates into pharmaceutical and fine chemical production lines, offering a tailored solution for precise granulation and mixing. Its innovative containment system ensures operator safety and product integrity by operating under hermetically sealed, negative pressure isolators. This equipment excels in producing pharmaceutical tablets and granules, cosmetic creams, and fine chemical compounds by facilitating essential processes such as mixing, granulation, and sampling with minimal exposure to contaminants. Designed for research, development, and pilot operations, it supports batch processing with flexibility in switching operations or conducting product testing mid-process. Compliance with OEB5 standards ensures high safety levels, while the inclusion of special transfer systems streamlines the charging and discharging of materials. Additionally, its construction allows for easy integration with existing systems, using a PLC-controlled interface for enhanced automation. Available customization options include additional scales, pumps, and mills to suit diverse production needs, all while maintaining efficient decontamination and minimal maintenance requirements.

Benefits

  • Enhances operator safety and product quality with hermetically sealed containment systems.
  • Boosts production flexibility by allowing process adjustments and sampling without contamination risk.
  • Ensures regulatory compliance with OEB5 standards for secure pharmaceutical processing.
  • Streamlines material flow and reduces handling time with specialized transfer systems.
  • Customizable integrations minimize changeover times and improve process efficiency.

General


Applications
Fine chemicals,Pharmaceutical tablets,Pharma solids,Granules,Cosmetics,Inhalates
End products
Coated tablets,Inhalation powders,Cosmetic creams,Fine chemical compounds,Cosmetic powders
Steps before
Charging auxiliary materials,Pre-dough preparation,R,D formulation
Steps after
Decontamination,Packing,Tablet pressing,Product testing,Sampling
Input ingredients
auxiliary materials,pre-dough starters,starter cultures
Output ingredients
granules,inhalates,tablets,finished products
Market info
Diosna is known for its expertise in manufacturing industrial dough mixing machines and systems, primarily for the bakery and food industries, showcasing a strong reputation for innovation, quality, and reliable engineered-to-order mixing solutions.

Technical Specifications


Containment Level
OEB5
Handling Type
Easy and Comfortable
Batch Type
Single-use for smaller batches
Pressure Handling
Negative pressure in isolators

Operating Characteristics


Batch vs. continuous operation
Batch
Automation level
User-friendly / single-use equipment for small batches
Containment method
Hermetically sealed isolators
Cleaning method
Decontamination after each process
Flexibility
Highly flexible,allows process interruption/change at any time
Safety standards
Compliance with regulations like OEB5
Charging/discharging systems
Special transfer systems for auxiliary materials and finished products

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Compact
Feed/discharge method
Special transfer systems for charging and discharging
Isolation system
Hermetically sealed isolators
Isolator interior customization
Scales,pumps,and mills

Custom Options


Control panel type
HMI / PLC
Integration possibilities
SCADA / DCS
Modular design
Yes/No
Scalability
Customizable batch sizes
Isolation system customization
Flexible layout options
Transfer system options
Customized for materials
Interior customization
Addition of scales,pumps,mills