Containment solutions for pharmaceutical production
Enhance operator safety and product integrity with advanced containment solutions, ensuring precise handling of sensitive materials during granulation and mixing processes in pharmaceutical production.

Granulates and Mixes Pharmaceutical Compounds
The containment mixer granulator from DIOSNA seamlessly integrates into pharmaceutical and fine chemical production lines, offering a tailored solution for precise granulation and mixing. Its innovative containment system ensures operator safety and product integrity by operating under hermetically sealed, negative pressure isolators. This equipment excels in producing pharmaceutical tablets and granules, cosmetic creams, and fine chemical compounds by facilitating essential processes such as mixing, granulation, and sampling with minimal exposure to contaminants. Designed for research, development, and pilot operations, it supports batch processing with flexibility in switching operations or conducting product testing mid-process. Compliance with OEB5 standards ensures high safety levels, while the inclusion of special transfer systems streamlines the charging and discharging of materials. Additionally, its construction allows for easy integration with existing systems, using a PLC-controlled interface for enhanced automation. Available customization options include additional scales, pumps, and mills to suit diverse production needs, all while maintaining efficient decontamination and minimal maintenance requirements.
Benefits
- Enhances operator safety and product quality with hermetically sealed containment systems.
- Boosts production flexibility by allowing process adjustments and sampling without contamination risk.
- Ensures regulatory compliance with OEB5 standards for secure pharmaceutical processing.
- Streamlines material flow and reduces handling time with specialized transfer systems.
- Customizable integrations minimize changeover times and improve process efficiency.
- Applications
- Fine chemicals,Pharmaceutical tablets,Pharma solids,Granules,Cosmetics,Inhalates
- End products
- Coated tablets,Inhalation powders,Cosmetic creams,Fine chemical compounds,Cosmetic powders
- Steps before
- Charging auxiliary materials,Pre-dough preparation,R,D formulation
- Steps after
- Decontamination,Packing,Tablet pressing,Product testing,Sampling
- Input ingredients
- auxiliary materials,pre-dough starters,starter cultures
- Output ingredients
- granules,inhalates,tablets,finished products
- Market info
- Diosna is known for its expertise in manufacturing industrial dough mixing machines and systems, primarily for the bakery and food industries, showcasing a strong reputation for innovation, quality, and reliable engineered-to-order mixing solutions.
- Containment Level
- OEB5
- Handling Type
- Easy and Comfortable
- Batch Type
- Single-use for smaller batches
- Pressure Handling
- Negative pressure in isolators
- Batch vs. continuous operation
- Batch
- Automation level
- User-friendly / single-use equipment for small batches
- Containment method
- Hermetically sealed isolators
- Cleaning method
- Decontamination after each process
- Flexibility
- Highly flexible,allows process interruption/change at any time
- Safety standards
- Compliance with regulations like OEB5
- Charging/discharging systems
- Special transfer systems for auxiliary materials and finished products
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Feed/discharge method
- Special transfer systems for charging and discharging
- Isolation system
- Hermetically sealed isolators
- Isolator interior customization
- Scales,pumps,and mills
- Control panel type
- HMI / PLC
- Integration possibilities
- SCADA / DCS
- Modular design
- Yes/No
- Scalability
- Customizable batch sizes
- Isolation system customization
- Flexible layout options
- Transfer system options
- Customized for materials
- Interior customization
- Addition of scales,pumps,mills