Virus filtration systems for biologics processing
Ensure efficient virus retention in biopharmaceutical production by integrating modular filter holders and single-use flow paths designed for scalability and precise control.

Filters and Retains Viruses in Biopharmaceutical Products
The Viresolve®Pro Virus Filtration System with Magnus Holders from the Viresolve® line provides a robust solution for biopharmaceutical manufacturers seeking reliable viral clearance. It uses specialized virus filter holders and modular filter systems ideal for monoclonal antibodies (mAbs), therapeutic proteins, and mRNA-based vaccines production. The system effectively integrates prefiltration and virus retention processes to ensure consistent viral safety across various production scales, from pilot to large-scale operations. Featuring a single-use flow path design, it minimizes risk of contamination while simplifying changeovers. This system supports scalable operations and adapts to evolving process requirements, making it indispensable in modern biopharma manufacturing. Designed to comply with industry standards, it facilitates both manual and modular operation modes, ensuring versatility in cleaning and maintenance.
Benefits
- Ensures comprehensive viral clearance to meet stringent biopharmaceutical safety standards.
- Adapts to changing production needs with scalable configurations from pilot to large-scale operations.
- Enhances operational efficiency with quick and easy system setup and changeovers.
- Minimizes contamination risks with single-use flow path systems.
- Supports compliance with industry regulations for safe and effective biopharma manufacturing.
- Applications
- Mab development,Protein biology,Biologics manufacturing,Biopharmaceuticals,Pharmaceutical manufacturing,Mrna development
- End products
- Biopharmaceutical formulations,Gene therapy products,Mrna-based vaccines,Monoclonal antibodies (mabs),Biologics such as enzyme replacement therapies,Viral vector vaccines,Therapeutic proteins
- Steps before
- Chromatography,Chemical Treatment
- Steps after
- Sterilization
- Input ingredients
- biologics feed streams,mAbs process feed,viral particles
- Output ingredients
- retained viruses,virus-free biologics,filtered biologics product
- Market info
- Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.
- Processing Efficiency
- High
- Scalability
- 6x scalability
- Automation
- Simple manual hydraulics
- Footprint
- Minimized holder footprint
- Vertical Orientation
- Yes
- Flow Path
- Single-use flow path
- Setup Time
- Fast setup
- Holder Configuration
- Modular format
- Loading and Unloading
- Quick and easy
- Loading rods
- Multiple lengths
- Scalability
- 1 to 30 Pod filters
- Loading and unloading
- Quick and easy
- Module format
- Modular for 6x scalability
- System adaptability
- Maximum adaptability with single-use flow paths
- Footprint
- Minimized with vertical orientation
- Flow path design
- Optimized single-use
- Hydraulics
- Simple manual
- Integration capability
- Flexible and easy-to-use filter holders
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Minimized holder footprint with vertical orientation
- Loading and unloading
- Quick and easy
- Discharge method
- No product contact
- Holder design
- Vertical orientation
- Rod length
- Multiple lengths for various sized installations
- Construction
- Robust construction
- Modular format
- Scalable within the same footprint
- Flow path design
- Optimized single-use
- Configuration
- Modular,allows as few as one filter
- Modular format
- 6x scalability within the same footprint
- Pod configuration
- 1 to 30 Pod filters
- Holder type
- Viresolve®Pro Magnus,Pro+,Shield H
- Flexibility
- Easy reconfiguration for scale up/down
- Flow path design
- Single-use for adaptability
- Footprint
- Minimized,vertical orientation
- Rod length
- Multiple lengths for various installations
- Hydraulics
- Simple manual
- Flow path assembly
- Optimally designed Flexware® assemblies
- Installation adaptability
- Fast setup of hardware