Single-use bioreactor for pilot and production scale
Streamline your bioprocessing with a scalable single-use solution that simplifies cultivation and mixing while minimizing contamination risk, ideal for achieving consistency across pilot to production scales.

Facilitates Scalable Single-Use Bioprocessing
The SUPR from Getinge Applikon is a single-use production reactor designed for bioprocessing applications in the biopharmaceutical industry. Leveraging the Click-n-Go system for rapid setup, it simplifies cultivation and sampling, ideal for monoclonal antibody production, CAR-T cell therapies, and mRNA vaccines. It supports seamless scaling from R&D to production, utilizing 50 to 250-liter containers, with a 1000-liter option forthcoming. Constructed from USP Class VI certified materials, it eliminates cross-contamination and minimizes cleaning requirements through gamma irradiation. The SUPR integrates easily with existing systems, offering compatibility with DeltaV™ DCS and Siemens PLCs. It complies with cGMP standards, ensuring quality and regulatory alignment for biotechnological applications.
Benefits
- Streamlines bioprocessing with Quick Click-n-Go system for faster setup times.
- Eliminates cross-contamination risks through single-use, gamma-irradiated components.
- Enables seamless scale-up from pilot to production with flexible volume options.
- Minimizes labor costs and reduces setup time with no cleaning validation required.
- Ensures regulatory compliance with cGMP-certified operations.
- Applications
- Vaccines, Cell and gene therapies, Biopharmaceuticals, Mabs, Diagnostics
- End products
- Car-t cell therapy products, Monoclonal antibodies, Mrna vaccines, Elisa test kits, Pcr diagnostic kits
- Steps before
- R, D, Process optimization, Sterilization setup, Assembly
- Steps after
- Scale-up, Gamma irradiation, Biological product contact, Documentation under cGMP conditions
- Input ingredients
- single-use cultivation container, Click-n-Go bag, optical DO sensor InSUS 607, pH sensor InSUS 310, 50-liter container, 250-liter container
- Output ingredients
- cell and gene therapies, monoclonal antibodies (mABs), vaccines, diagnostics
- Market info
- Getinge is known for providing innovative healthcare and life sciences products, specializing in medical technology, infection control, surgical workflows, and critical care solutions. They maintain a strong reputation for quality and technological advancement in these sectors.
- Total volume
- 7-1356 L
- Working volume
- 50-250 L
- Minimum working volume
- 10-50 L
- Aspect ratio total volume
- 1.7
- Aspect ratio working volume
- 1.24-1.23
- Bottom
- Dished bottom
- Impellers
- Marine with 152 mm diameter / Marine with 260 mm diameter
- Sparger
- Drilled hole sparger
- Sterilization
- Gamma irradiation >25 kGy
- Ports
- Sample port, Temperature pocket, Single-use Optical DO sensor, Single-use pH sensor
- Special port
- Drain to Bottom port with CPC MPX connector
- Container size
- 50-1000 L
- Sterilization method
- Gamma irradiation
- Bag loading system
- Click-n-Go
- Scalability
- Pilot to production scale
- Automation level
- Manual / PLC / SCADA
- Cleaning method
- No cleaning required
- Contamination prevention
- No risk of cross-contamination
- Installation method
- Click and lock system
- Biological compatibility
- USP Class VI plastics
- Cleanability
- No cleaning required
- GMP Compliance
- cGMP
- FDA materials
- USP Class VI plastics
- Sterilization Standard
- Gamma Irradiation >25 kGy
- Container Volume
- 50 L / 250 L
- Aspect ratio total volume
- 1.7
- Bottom type
- Dished bottom
- Impeller type
- Marine with 152 mm diameter / Marine with 260 mm diameter
- Sparger type
- Drilled hole sparger
- Sterilization method
- Gamma irradiation >25 kGy
- Control panel type
- Intuitive interface
- Integration possibilities
- Compatible with DeltaV™ DCS, Siemens, Allen Bradley PLCs
- Container size options
- 50 L, 250 L, 1000 L
- Impeller type
- Height adjustable impeller
- Sterilization method
- Gamma irradiation
- Sparger type
- Drilled hole sparger
- Sensor options
- Single-use Optical DO sensor, single-use pH sensor
- Port configuration
- Sample port + Temperature pocket