Benchtop tangential flow filtration system

Ensure high-purity yields and streamline your filtration processes with this benchtop tangential flow system, ideal for compact lab environments seeking efficient liquid handling and precise separation capabilities.

Processes Filtration, Separation, and Purification

The TFF KRONOS from Solaris is a benchtop Tangential Flow Filtration System tailored for diverse applications in the biotech, pharmaceutical, and chemical industries. Designed to integrate smoothly into laboratory and development environments, it excels in filtration, separation, ultrafiltration, microfiltration, and diafiltration processes, accommodating volumes from 2L to 10L. It features a robust, autoclavable glass vessel with flexible membrane options like hollow fiber, cassettes, and ceramic for optimal performance across a 0.5 m² filtration area. Equipped with a precision brushless motor, the TFF KRONOS offers variable speeds from 1 to 2000 RPM, ensuring consistent processing. Its modular design supports batch and fed-batch operations, with automation handled by Modbus-connected sensors and an intuitive SCADA Lab View software, guaranteeing seamless process control and data integrity (CFR21 part 11 compliant). Additional features like integrated NPW testing, automated filtrate flow control, and comprehensive filter history management underscore its efficiency and reliability. Constructed to cGMP standards, the TFF KRONOS promises easy maintenance, accommodating various industry needs with options for advanced filter material selection, and specialized engineering support from Solaris technicians, ensuring alignment with specific operational parameters.

Benefits

  • Enhances purification precision for biopharmaceuticals and APIs, ensuring high product quality.
  • Increases operational efficiency with customizable process sequences and remote monitoring.
  • Minimizes lab space usage with its compact footprint.
  • Meets stringent industry standards with cGMP construction and CFR21 part 11 compliance.
  • Provides flexible filtering options to accommodate varying separation needs.

General


Applications
Fine chemicals,Nutraceuticals,Biopharmaceuticals,Enzymes,Pharmaceuticals
End products
Insulin,Active pharmaceutical ingredients (apis),Monoclonal antibodies,Proteases,Herbal extracts,Dietary supplements
Steps before
Preparation of feed solution,Pre-filtration,Adjustment of pH
Steps after
Concentration,Diafiltration,Sterilization
Input ingredients
feed solution,liquid mixture
Output ingredients
permeate,retentate,concentrate,filtrate
Market info
Solaris Biotech is known for manufacturing specialized engineered-to-order bioprocessing equipment, including fermenters and bioreactors, with a strong reputation for innovation, quality, and customization capabilities in the biotechnology and pharmaceutical markets.

Technical Specifications


Volume
2L,5L,10L
Filtration Area
Up to 0.5 m²
Membrane Types
Hollow fiber,cassettes,ceramic
Motor Speed
1 to 2000 RPM
Optional Flow Control
Filtrate flow control
Automation
Automated process sequence

Operating Characteristics


Batch vs. continuous operation
Batch / Inline Continuous
Automation level
SCADA / PLC controlled
CIP/SIP
Autoclavable glass vessel
Cleaning method
Autoclavable / Manual
Integrated steps
Automated process sequence
Working mechanism
Tangential Flow Filtration
Changeover time
Flexible filter holders
Energy efficiency
Smart sensors / low power
Air incorporation control
Integrated NPW test

Material Compatibility


Cleanability
Autoclavable

Product type Characteristics


Application Range
Batch and fed batch ultrafiltration,microfiltration,diafiltration


GMP Compliance
cGMP

Physical Characteristics


Machine footprint
Small footprint to maximize lab space efficiency
Vessel type
Jacketed and autoclavable glass vessel
Capacity
Available in 3 volumes
Filtration area
Up to 0.5 m² total filtration area
Discharge method
Recirculation vessels and valves module conveniently located
Motor type
Powerful and accurate brushless motor,from 1 to 2000 RPM
Filter holders
Flexible filters holders

Custom Options


Control panel type
Modbus digital sensors
Flexibility in membrane types
Hollow fiber,cassettes,ceramic
Integration possibilities
Wireless connection,remote access
Volume options
2L,5L,10L
Filtration area
Up to 0.5 m²