Single-use bioreactor for cell culture processes
Optimize your cell culture productivity with advanced mixing dynamics that support high cell density processing, perfect for scaling up from pilot to commercial production with reduced contamination risk.

Optimizes Cell Culture and Mixing Processes
The DynaDrive Single-Use Bioreactor from Thermo Scientific is designed to revolutionize biopharmaceutical manufacturing, offering unmatched flexibility for cell culture and mixing processes. Central to its operation is a stir tank design that efficiently accommodates batch, fed-batch, and perfusion processes. It supports biopharmaceutical applications including monoclonal antibodies and viral vectors for gene therapy, managing from pilot to commercial-scale production with capacities up to 5,000 liters. Ergonomically designed for ease of use, the bioreactor features an open-architecture system compatible with various control frameworks, ensuring seamless integration into existing production lines. Thermo Scientific’s robust Aegis 5-14 bioprocessing film is utilized for bioprocess containers, combining agility with durability. The system supports highly regulated environments, adhering to BPOG guidelines for leachables and extractables, and it offers streamlined seed train processes to minimize contamination risks. Furthermore, its design prioritizes efficiency with optimized mixing dynamics and an energy-efficient drive train, ensuring reliable operation at high cell densities.
Benefits
- Enhances production scalability from pilot to commercial stages, ensuring seamless transition.
- Reduces contamination risks with advanced seed train process optimization.
- Integrates easily into existing systems with open-architecture compatibility.
- Achieves higher cell concentrations efficiently, supporting demanding bioproduction needs.
- Complies with stringent regulatory standards, ensuring safety and quality.
- Applications
- Biopharmaceuticals,Gene therapy products,Cell culture products
- End products
- Car-t cell therapies,Monoclonal antibodies,Viral vectors for gene therapy,Cellular immunotherapies,Recombinant proteins
- Steps before
- Cell Culture,Seed Train Preparation,Media Preparation
- Steps after
- Harvesting,Protein Purification,Downstream Processing
- Input ingredients
- cell culture media,cells,nutrients,oxygen
- Output ingredients
- bioproducts,protein,biomass
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Capacity
- 500 L
- Capacity (English)
- 132 gal
- Height
- 9 ft. 9 in.
- Height (Metric)
- 3 m
- Length
- 2 ft. 7 in.
- Length (Metric)
- 82 cm
- Width
- 2 ft. 7 in.
- Width (Metric)
- 81 cm
- Material
- Stainless Steel
- Mixing Dynamics
- Optimized for modern cell culture
- Turndown Ratio
- 20
- Power Input per Volume (PIV)
- Optimized
- KLa Performance
- Optimized for modern processes
- Cell Density
- >100 million cells/mL
- Working mechanism
- Stir-tank design
- Integrated steps
- Mixing and mass transfer optimization
- Batch vs. continuous operation
- Batch,fed batch,and perfusion cultures
- Automation level
- Interoperability with control systems
- Cleaning method
- CIP
- Energy efficiency
- Optimized PIV and kLa performance
- Seed train process
- 10
- Usage
- Batch,fed batch,and perfusion cultures
- Material
- Stainless Steel
- Machine footprint
- 2 ft. 7 in. x 2 ft. 7 in.
- Control panel type
- Open-architecture,interoperable
- Integration possibilities
- Interoperable with available control systems
- Scale options
- 50 L,500 L,3000 L,5000 L
- Sparging approach
- Redesigned for optimized performance
- Drive train integration
- Integrated in BPC
- Film material
- Thermo Scientific Aegis 5-14 bioprocessing film