Pharma extraction clarifier
Achieve superior purity in pharma extraction with efficient separation of solids and liquids, seamlessly integrating into your production line while ensuring high yield and low solvent use.
Clarifies and Separates Liquid-Solid Suspensions
GEA’s Hydrohermetic Pharmaceutical Clarifier excels in liquid-solid extraction processes, especially for the pharmaceutical and biotechnological sectors. Designed with a patented hydrohermetic feed system, it minimizes shear forces, enhancing gentle handling and reducing contamination risks. The clarifier supports fully automatic, continuous operations, making it ideal for separating active pharmaceutical ingredients (APIs), monoclonal antibodies, and essential oils. Operating on the co-current, counter-current, or cross-current principles, it optimizes phase separation efficiency. With CIP capability, it ensures thorough cleaning without process disruption. Additionally, it delivers significant savings with lower solvent requirements and reduced operating costs, while high stage efficiency minimizes investment by requiring fewer stages. Constructed to meet GMP standards, it is available in corrosion-resistant materials to maintain chemical integrity.
Benefits
- Enhances product purity with low shear forces, minimizing contamination risks.
- Reduces operating and solvent costs with efficient phase separation processes.
- Maximizes yield and throughput with optimized space utilization.
- Ensures process compliance and safety with GMP-compliant construction.
- Simplifies maintenance and cleaning through fully integrated CIP systems.
- Applications
- Liquid formulations,Fine chemicals,Nutraceuticals,Biopharmaceuticals,Pharmaceuticals
- End products
- High-purity enzymes,Active pharmaceutical ingredients (apis),Monoclonal antibodies,Solvent-based drug formulations,Herbal extracts,Natural flavor extracts,Nutrient-infused liquid solutions,Liquid supplements,Biotechnological vaccines,Essential oils
- Steps before
- Suspension Preparation
- Steps after
- CIP (Cleaning-In-Place),Quality Control,Packing
- Input ingredients
- suspensions with low solid contents,solid-liquid mixtures,pharmaceutical suspensions
- Output ingredients
- clarified liquids,reduced solid content,pharmaceutical extracts
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Solid Content
- Up to 7% by vol.
- Automation
- Fully automatic cleaning-in-place (CIP)
- Control System
- Controlled partial ejections
- Stage Efficiency
- High stage efficiency
- Contact Time
- Short contact times
- Throughput Capacity
- Optimum throughput capacity
- Shear Forces
- Low shear forces
- Working mechanism
- Centrifugal separation
- Integrated steps
- Controlled partial ejections
- CIP Principles
- Fully automatic CIP
- Batch vs. continuous operation
- Continuous
- Automation level
- Fully automated
- Feed system
- Hydrohermetic feed
- Stage operation
- Co-current,counter-current,cross-current principles
- Solvent requirement
- Low
- Space requirement
- Minimum
- Process security
- High
- Yield quality
- Higher yield
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Tank shape and size
- Designed for low solid content (up to approx. 7% by vol.)
- Feed method
- Hydrohermetic feed system
- Discharge method
- Partial ejections
- Compact footprint
- Optimized for minimum space requirement
- Control System
- PLC / SCADA
- Feed System
- Hydrohermetic
- Ejection System
- Controlled Partial Ejection
- Cleaning Method
- Fully Automatic CIP