Automated cell manufacturing system for stem cells
Scaling up the production of pluripotent stem cells (PSCs) requires maintaining their pluripotency and differentiation capacity while minimizing human intervention and variability. Ensuring consistent cell culture conditions is a major challenge in expanding these cells for research or clinical use.
Automate and standardize cell culture workflows
The Marty by Unicorn Biotechnologies is a fully closed and automated cell manufacturing system designed to standardize and scale up cell culture workflows. It integrates fluidics, mechanical actuation, environmental controls, and in-line biochemical sensing into a single system. The system is equipped with a gas and temperature-controlled incubator and a refrigerated on-board reagent storage unit, connecting parallelized cell culture vessels. Marty uses adaptive process controls driven by machine intelligence to optimize cell culture conditions in real time. It is suitable for both anchorage-dependent and suspension-based cell lines, including iPSCs, MSCs, and ES cells. The system’s design reduces the need for manual labor by over 80% and decreases process failures by more than 50%, while developing bioprocesses in under six months.
Benefits
- Reduces manual labor by over 80%
- Decreases process failures by more than 50%
- Real-time optimization with adaptive process controls
- Supports both anchorage-dependent and suspension-based cell lines
- Accelerates bioprocess development in under six months