Industrial universal reactor for large-scale chemical synthesis

For chemical producers scaling past laboratory setups, this versatile reactor safely handles large-batch reactions under a broad range of temperatures and pressures, ensuring precise control and efficient processing of complex formulas.

Synthesizes, Distills, and Mixes Large-Scale Chemical Reactions

The QVF Universal-Reactor from De Dietrich Process Systems is your go-to solution for scaling up chemical reactions that exceed lab-scale capabilities. Designed for the pharmaceutical, fine chemicals, and specialty chemicals sectors, it allows for precise control in synthesizing active pharmaceutical ingredients, monoclonal antibodies, specialty polymers, and more. By employing a versatile, inert gas-compatible design, this reactor excels in handling liquid and gas processes under vacuum and EX-rated conditions. It facilitates seamless integration into existing lines with its robust, digitally controlled stirrer and OptiMix® baffle system, offering extraordinary mixing performance without splashing. Featuring a borosilicate glass construction and PTFE components, it ensures optimal chemical resistance and longevity. The reactor is equipped with CIP-nozzles, ensuring easy and reliable cleaning between batches, thus minimizing downtime. Compliance with European EX regulations guarantees safe operation in volatile environments. Whether for pilot studies or full-scale production, you can request custom configurations to best meet your specific operational needs.

Benefits

  • Enhances scalability for production beyond lab capabilities, supporting larger batch sizes.
  • Ensures safety in volatile environments with EX-rated design and materials.
  • Reduces downtime with efficient cleaning via CIP system.
  • Optimizes reaction control with precise temperature and mixing adjustments.
  • Maintains chemical integrity with corrosion-resistant borosilicate glass and PTFE construction.

General


Applications
Specialty chemicals, Agricultural chemicals, Fine chemicals, Bio-pharmaceuticals, Precious metal, Pharmaceuticals
End products
Active pharmaceutical ingredients (apis), Agrochemicals, Monoclonal antibodies, Specialty polymers, High-purity gold, Catalyst complexes, Platinum group metal compounds
Steps before
Mixing, Reactant Addition, Vacuum Application, Inert Gas Preparation, Jacketed Vessel Tempering
Steps after
Distillation, Temperature Control, Vacuum Distillation, Product Transfer, Cleaning via CIP-Nozzles
Input ingredients
reactants, inert gas, light boiling components, thermo liquids
Output ingredients
light boiling components, distillate receiver, solvents, temperature sensitive products
Market info
De Dietrich is renowned for manufacturing high-quality engineered-to-order (ETO) equipment, specializing in chemical process systems, glass-lined reactors, and filtration technologies, with a strong reputation for innovation, reliability, and safety in the chemical and pharmaceutical industries.

Technical Specifications


Temperature Range
-50°C to 200°C
Operating Pressure
up to +0.5 barg
Material
Borosilicate Glass 3.3
Stirrer Drive
Electric motor with adjustable gearbox
Cleaning Method
CIP via CIP-nozzles
Distillation Capability
Light boiling components
Automation
Manual adjustment

Operating Characteristics


Working Mechanism
Batch synthesis with inert gas
Temperature Range
-20°C to +150°C
Pressure Control
Inert gas overpressure up to +0.5barg
Vacuum Operation
Yes, with vacuum and overpressure operation
Cleaning Method
CIP with self-draining construction
Mixing Performance
OptiMix® baffle system
Distillation Capability
Light boiling component distillation
Automation Level
EX-rated instrumentation for automated operation
Heating/Cooling Integration
Jacketed vessel with a thermo liquid

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine Footprint
Compact
Reactor Shape
Jacketed Vessel
Reactor Size
Customizable
Discharge Method
Distillation/Withdrawal
Feed Method
Handhole and Vacuum Feed
Construction Material
Borosilicate Glass 3.3
Stirrer Drive
Robust Electric Motor
Temperature Control
Thermo Liquids
Pressure Control
Max +0.5barg
Seal Type
Single Mechanical Seal
Cleanability
CIP Nozzles
Baffle System
OptiMix® Baffles

Custom Options


OptiMix Baffles
Triple-walled reactor
Vacuum connection
Including pressure release valve and bursting disc
CIP-Nozzle
Made of PTFE or stainless steel