Industrial GMP freeze dryer
Optimize the lyophilization of sensitive pharmaceutical compounds with a machine designed for precise nucleation control, ensuring consistent product quality and stability over time.
Freeze-Dries and Stabilizes Pharmaceutical Products
The LYOMAX Industrial Freeze Dryer from IMA Life is engineered for precise lyophilization of biopharmaceuticals and sterile injectables, including vaccines and monoclonal antibodies. Utilizes advanced nucleation control through VERISEQ® technology to maintain product stability. Features configurable designs with shelf areas from 1 m² to 100 m², catering to varying production demands. The FUSION™ shelves reduce weight by 20%, enhancing thermal efficiency during freeze-drying processes. Equipped with PAT tools, it ensures reduced process time and energy consumption. Compliance with GAMP, cGMP, and FDA standards ensures alignment with global regulatory requirements. Customizable automation options support manual, semi-automatic, and automatic operations, seamlessly integrating into existing production lines. Designed with optional eco-friendly KryoAir refrigeration for minimized environmental impact. Available materials include corrosion-resistant stainless steel, offering durability in operation.
Benefits
- Achieves precise product stability with advanced nucleation control, ensuring consistent quality.
- Reduces energy costs up to 20% with patented FUSION™ shelf technology.
- Minimizes environmental impact with eco-friendly KryoAir refrigeration.
- Ensures regulatory compliance with GAMP, cGMP, and FDA standards.
- Versatile customization accommodates diverse production scales and integration needs.
- Applications
- Lyophilized products,Biopharmaceuticals,Sterile injectables,Pharmaceutical products
- End products
- Vaccines,Blood plasma products,Hormone therapies,Insulin,Cancer therapeutics,Monoclonal antibodies,Antibiotics
- Steps before
- Solution Preparation,Emulsification,Filling into Containers,Pre-freezing
- Steps after
- Sterilization,Sealing,Packaging
- Input ingredients
- solvent,unstable materials,active ingredient,liquid nitrogen,refrigerants
- Output ingredients
- dried drug product,stable drug product,lyophilized products
- Market info
- IMA is known for its expertise in manufacturing automated packaging machines and solutions, particularly for the pharmaceutical, cosmetics, food, tea, and coffee industries, offering innovative, high-quality equipment and comprehensive customer service.
- Machine sizes
- 1 m2to 100 m2
- Configuration options
- Integral condenser,external condenser,two-story,pass through
- Compressor type
- Two stage reciprocating semi-hermetic/screw compressors
- Refrigeration system
- Liquid nitrogen
- Shelf cooling temperature
- -55°C to -70°C
- Condenser cooling temperature
- -75°C to -120°C
- Refrigerants
- HFC/LN2
- Loading/unloading systems
- Integrated automatic,semi-automatic,manual
- Vacuum measurement
- Capacitance manometers
- Advanced nucleation technology
- VERISEQ,reg
- Using sterile liquid nitrogen
- Shelf construction
- IMA Life FUSION™ - FUSION PLUS™ technology
- Shelf weight reduction
- 20%
- Refrigeration temperature (KryoAir)
- as low as -100°C
- Shelf spacing range
- 80 to 140 mm
- Compressor power
- 2 x 5 hp to 4 x 50 hp
- Vacuum pumping capacity
- 1 x 28 m3/h to 2 x 275 m3/h
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP 121°C / SIP 135°C
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Cleaning method
- CIP
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine sizes
- 1 m² to 100 m²
- Configurations
- Integral condenser,external condenser,two-story,pass through designs
- Shelf size
- Varies based on model (455 x 165 mm to 1,524 x 1,830 mm)
- Shelf spacing range
- 80 to 140 mm
- Condenser capacity
- Varies based on model (e.g.,272 kg to 756 kg at 12.7 mm ice)
- Compressor type
- Reciprocating semi-hermetic/screw compressors/liquid nitrogen
- Cooling temperatures
- Shelf cooling to -55/70°C,condenser cooling to -75/120°C
- Loading/unloading systems
- Integrated automatic,semi-automatic,and manual
- Configurable options
- Integral condenser,external condenser,two-story,pass through designs
- Shelf technology
- FUSION™ - FUSION PLUS™ shelves
- Shelf size
- 455 x 165 mm to 1,524 x 1,830 mm
- Shelf spacing
- 80 to 140 mm
- Refrigeration system
- Two stage semi-hermetic/screw compressors or liquid nitrogen
- Loading/unloading systems
- Integrated automatic,semi-automatic,manual
- Machine sizes
- 1 m² to 100 m²