Single-use bioreactor for high volume cell cultures
For optimizing cell culture efficiency, this advanced bioreactor revolutionizes your production with scalable single-use technology, providing unmatched mixing and mass transfer performance.

Cultures Cells and Expresses Proteins
The DynaDrive Single-Use Bioreactor, engineered by Thermo Fisher Scientific, revolutionizes the bioprocessing workflow for pharmaceutical manufacturers and biotechnology companies. Its innovative stir-tank design features a reengineered mixing impeller and sparging system that optimizes mixing dynamics and mass transfer, critical for demanding cell cultures. This bioreactor excels in applications such as monoclonal antibody production, recombinant proteins, and gene therapies, delivering scalability from 50 to 5,000 liters, making it adaptable for pilot-scale to commercial production.
Engineered for efficiency, the DynaDrive reduces seed-train turndown ratios with a 10:1 and 20:1 ratio for 50 L and 500 L reactors respectively, minimizing contamination risk. Equipped with load cells for precise measurement and constructed with robust Thermo Scientific Aegis 5-14 bioprocessing film, it ensures durability and high performance. The open-architecture design allows seamless integration with existing control systems, enhancing operational efficiency. Fully compliant with BioPhorum Operations Group (BPOG) guidelines for leachable and extractable safety, it supports rigorous regulatory standards crucial for life sciences applications, ensuring reliability in biopharmaceutical production environments.
Benefits
- Enhances productivity with scalable volumes from pilot to commercial scale.
- Minimizes contamination risk through reduced seed-train turndown ratios.
- Facilitates efficient cell culture with optimized mixing and mass transfer.
- Integrates easily with existing systems due to open-architecture design.
- Complies with safety guidelines, ensuring reliability in regulated environments.
- Applications
- Cell and gene therapy,Biopharmaceuticals,Nutraceuticals,Protein expression
- End products
- Viral vectors,Monoclonal antibodies,Protein supplements,Vaccine components,Cell-based therapeutics,Gene therapies,Recombinant proteins
- Steps before
- Cell Culture Preparation,Media Preparation,Seed Train Development
- Steps after
- Harvesting,Protein Expression Analysis,Purification
- Input ingredients
- cell culture media,single-use bioprocess container,seed culture
- Output ingredients
- biomass,protein expression products
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Capacity
- 500 L
- Height (Metric)
- 3 m
- Width (Metric)
- 81 cm
- Length (Metric)
- 82 cm
- Material
- Stainless Steel
- Power Input per Volume (PIV)
- Optimized for modern cell culture processes
- KLa Performance
- Optimized for modern cell culture processes
- Seed Train Process
- 10
- Scalability
- 50 L to 5,000 L
- Max Cell Density
- >100 million cells/mL
- Sparging Approach
- Redesigned for optimization
- Working Mechanism
- Revolutionary stir-tank design
- Batch vs. continuous operation
- Batch,fed batch,and perfusion cultures
- Seed-train turndown ratio
- 10
- Mixing Dynamics
- Optimized for modern cell culture processes
- Interoperability
- Open-architecture approach with control systems
- Cleaning Method
- Leachable and extractable (L,E) evaluated
- Density/particle size
- 0.5–2.5 g/cm³
- Tank shape and size
- Stir-tank design,500 L capacity
- Material
- Stainless Steel
- Height
- 9 ft. 9 in. / 3 m
- Length
- 2 ft. 7 in. / 82 cm
- Width
- 2 ft. 7 in. / 81 cm
- Control System Integration
- Interoperable with available control systems