Nested syringe filling and stoppering line
Streamline your aseptic filling process with advanced machinery that handles nested syringe tubs efficiently, ensuring sterile conditions and precise operations from debagging to stoppering.
Prepares and Processes Nested Syringes and RTU Vials
The FREETUB Series by Marchesini Group is a pivotal component in the aseptic filling of nested syringes and ready-to-use vials. It automates the critical pre-processing steps such as tub debagging, de-liding, and de-lining, ensuring sterile environments and protecting sensitive biopharmaceuticals, vaccines, and pharmaceuticals.
Designed for integration into pharmaceutical and biotech production lines, it efficiently manages the handling of insulin syringes, prefilled epinephrine syringes, COVID-19 vaccines, and more. The system operates with both manual and automatic control options, providing flexibility across different production scales.
The FREETUB Series maintains sterility and precision with robust automation features, such as PLC control, automatic bag cutting, and robotized lid removal equipped with tear-proof mechanisms. It supports installation under various isolation technologies, including LAF, open RABS, closed RABS, or Isolator systems.
Engineered for meticulous sanitary standards, it allows manual intervention if necessary and includes mechanisms for tub rejection in case of faults. This equipment not only caters to high-throughput environments but also maximizes efficiency, thus meeting GMP and FDA regulatory standards.
Benefits
- Enhances productivity by automating sterile preparation processes, reducing manual intervention and error rates.
- Increases operational efficiency with versatile installation options under different isolator technologies.
- Ensures product integrity with robotized handling that minimizes contamination risks during aseptic filling.
- Meets stringent pharmaceutical standards with a design compliant with GMP and FDA requirements.
- Offers operational flexibility with both automatic and manual control capabilities for varied production needs.
- Applications
- Rtu cartridges,Vaccines,Pharmaceutical syringes,Biopharmaceuticals,Ready-to-use (rtu) vials
- End products
- Insulin syringes,Rtu lyophilized vials,Rtu antibiotic vials,Measles vaccines,Covid-19 vaccines,Oncology drugs,Disposable syringe kits,Preloaded anesthetic cartridges,Prefilled epinephrine syringes,Hepatitis b vaccines
- Steps before
- Tub Debagging,De-liding,De-lining,Bagged Tubs Loading
- Steps after
- Nested Syringe Filling,Stoppering,Tub Unloading,Lid and Liner Disposal
- Input ingredients
- Bagged Tubs,Sealed Tubs,Nested Syringe
- Output ingredients
- Open Tubs,Debagged Tubs,De-lidded Tubs,Sterile Tubs
- Market info
- Marchesini is renowned for manufacturing high-quality packaging machinery for the pharmaceutical and cosmetics industries, offering innovative, customized solutions with advanced automation and technology.
- Automation
- Manual / Automatic
- Loading System
- Manual and Automatic Options
- Bag Disposal
- Automatic
- Lid Removal
- Robotized with Tear-proof Movement
- Tub Unload System
- Positive Pushing System
- Faulty De-liding Handling
- Automatic Rejection / Manual Facility
- Installation Environment
- LAF / Open RABS / Closed RABS / Isolator
- Loading method
- Manual/Automatic
- Bag stretching station
- Automatic
- Gate operation
- Automatic
- Unloading system
- Positive pushing without contact
- Bag disposal
- Automatic
- Lid removal
- Robotized system
- Liner removal
- Automatic
- De-liding fault recovery
- Manual facility
- Tub orientation
- Rotatable if necessary
- Installation environment
- LAF/open RABS/closed RABS/Isolator
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Container size
- Standard nested syringe size
- Container type
- Nest / Tub
- Material type
- Plastic / Glass
- Heat sensitivity
- Sensitive
- Viscosity
- Low to high viscosity compatibility
- Sterility requirements
- Aseptic conditions
- Stoppering type
- Automatic / Manual
- Stopper material
- Rubber / Silicone
- Automation level
- Manual / Automatic
- Nesting method
- Pre-nested configurations
- Sterile handling
- Non-contact positive pushing
- Machine footprint
- Compact
- Feed/discharge method
- Positive pushing system
- Control panel type
- Robotized system
- Manual/Automatic operation options
- Available
- Installation environment
- LAF,RABS,or Isolator
- Control panel type
- HMI / PLC
- Integration possibilities
- Open/Closed RABS,Isolator
- Manual vs. Automatic operation
- Manual/Automatic