Cleaning in place systems for bioreactors

In biopharmaceutical manufacturing, ensuring all system components are free from contamination is critical to product safety and quality. A typical challenge is cleaning complex equipment configurations, including vessels, piping, and ancillary lines, without disassembly.

Automated cleaning of bioreactor components

The CIP systems by Bioengineering offer tailored and automated cleaning solutions for bioreactor components, ensuring thorough contamination removal. These systems can be either rigidly installed for large plants or mobile for smaller bioreactors, providing flexible operation. They employ advanced features such as programmable cleaning steps, circulation pumps, and heat exchangers for optimal performance. Integrated PLCs automate and document the cleaning process, adjusting steps dynamically for consistent cleanliness. The systems utilize a combination of mechanical components (e.g., spray balls, CIP lances) and chemical agents (e.g., NaOH, acids) tailored to specific needs. Additionally, they are designed to be economical and environmentally friendly by recycling cleaning solutions when cross-contamination is not an issue.

Benefits

  • Ensures comprehensive contamination removal
  • Flexible for both large and small scale operations
  • Automated and programmable for consistent results
  • Eco-friendly with cleaning solution recyclability
  • Customizable to specific hygiene requirements

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