Cleaning in place systems for bioreactors

Ensure seamless sanitization with a mobile cleaning system designed to maintain product purity in bioreactor operations, reducing downtime and enhancing operational efficiency.

Automates and Optimizes Cleaning Processes

The CIP-Mobile Cleaning System from Bioengineering AG is engineered to streamline and enhance sanitation processes across various industries, including biopharmaceuticals, food, and cosmetics. This system excels in its ability to automatically clean complex equipment like fermentors and bioreactors through a meticulously controlled sequence involving pre-rinsing, alkaline cleaning, and final rinsing. Designed with flexibility in mind, it includes up to 28 programmable cleaning steps and is equipped with dual 200-liter tanks, a circulation pump, heat exchangers, and robust parameters control such as temperature and flow rates. Ideal for tackling challenges in operations ranging from pilot to large-scale production, this solution ensures surfaces in contact with products remain free of contaminants to avert cross-contamination. Constructed with high-grade materials, it supports recycling of cleaning solutions where applicable, promoting both economic and ecological benefits. The CIP-Mobile is compatible with industrial standards, featuring seamless integration with existing production lines through its PLC-controlled system, offering reliable documentation and control adjustments to meet stringent hygiene requirements.

Benefits

  • Prevents cross-contamination with thorough and programmable cleaning cycles.
  • Enhances operational efficiency with flexible deployment, accommodating both mobile and fixed installations.
  • Reduces downtime through automated, PLC-controlled sanitation processes.
  • Supports sustainability initiatives by allowing recycling of cleaning solutions.
  • Meets stringent hygiene standards with comprehensive documentation and process adaptability.

General


Applications
Food,Beverages,Chemicals,Homeopathy,Metallurgy,Nutritional products,Alternative medicine,Cosmetics,Biopharmaceuticals,Petrochemicals,Mining,Pharmaceuticals
End products
Herbal tinctures,Vaccines,Steel additives,Probiotic drinks,Solvents,Protein supplements,Tablets,Lotions,Gold extraction reagents,Beer,Plasticizers
Steps before
Media/Buffer Preparation,Component Dosing,Solution Mixing
Steps after
Final Rinsing,Blowing Out,Quality Assurance/Quality Control
Input ingredients
NaOH,acids,alkaline solution,cleaning agents,water for injection (WFI),piping,chemical substances,mixing tanks,dosage vessels
Output ingredients
clean surfaces,contaminant-free surfaces,recycled CIP solutions,recirculated rinsing liquids
Market info
Bioengineering is known for its expertise in designing and manufacturing customized bioreactors and fermenters, serving the biotechnology and pharmaceutical industries. They are reputed for high-quality, engineered-to-order solutions and innovative process technologies.

Technical Specifications


Cleaning steps
Up to 28 programmable steps
Tank Capacity
Two 200-liter tanks
Circulation pump
Yes
Heat Exchangers
For steam
Measurement and control parameters
Temperature,flow rates,conductivity
Automation
PLC-controlled
Recyclability
Recyclability of the cleaning solutions
CIP loops
Precisely defined for all transitional zones
Cleaning agents
Alkaline solution (2-3% NaOH)
Cleaning steps
Pre-rinsing,cleaning,rinsing,final rinsing,blowing out
Final rinsing
WFI (Water for Injection)

Operating Characteristics


Automation level
PLC / SCADA
CIP/SIP
CIP
Cleaning method
CIP / Manual
Batch vs. continuous operation
Batch / Inline
Integrated steps
Pre-rinsing,Alkaline Cleaning,Rinsing,Final Rinsing,Blowing Out
Energy efficiency
Optimized for economic and ecological processes
Working mechanism
Multiple tanks,circulation pumps,heat exchangers

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Custom Options


Control panel type
Programmable Logic Controller (PLC)
Integration possibilities
BioSCADA integration
Tank size
200 liters
Heat exchangers type
Steam