Pharmaceutical twin screw extruders
In pharmaceutical production, ensuring uniform mixing and minimizing degradation of active pharmaceutical ingredients (APIs) is crucial. Traditional batch processes can lead to inconsistencies and higher degradation rates, leading to inefficiencies and increased costs.
Continuous mixing and dispersion of Apis
The ZSK Pharma Extruder from Coperion excels in continuous mixing of pharmaceutical ingredients. Featuring a modular barrel design customizable to product needs, it ensures intensive mixing with minimized product degradation. The extruder utilizes high torque, accommodating high throughput rates while maintaining low product temperatures. Constructed in GMP design, it uses FDA-compliant materials for all product contact parts. With specific torque up to 18 Nm/cm³ and maximum speeds up to 1,200 rpm, the ZSK Pharma Extruder can handle throughputs from 1 to 10 kg/h in laboratory settings. The advanced control system simplifies operations, while the compact design facilitates easy cleaning and maintenance. Ideal for pharmaceutical hot melt extrusion and wet extrusion of APIs, this extruder is a versatile tool for enhancing product bioavailability and creating controlled-release formulations.
Benefits
- Uniform mixing and dispersion of APIs
- Minimized product degradation
- GMP-compliant and FDA-approved materials
- High throughput with low operational temperatures
- Easy to clean and maintain