Virus filtration system for biologics manufacturing
Ensure safe and effective biopharmaceutical production by integrating reliable virus filtration systems for efficient viral clearance, critical for downstream processing of therapeutic proteins and vaccines.

Ensures Viral Clearance in Bioprocessing
The Viresolve®Pro Solution from a leading manufacturer in virus filtration offers a robust system for achieving effective viral clearance in biopharmaceutical processes. Featuring a range of modular pod filter holders and single-use filtration systems, it efficiently handles filtration and viral clearance in applications such as monoclonal antibodies and mRNA vaccines. The system’s unique design ensures scalability from pilot to large-scale processes, maintaining flexibility with manual and process-scale options.
The Viresolve®Pro’s workflow operates with pod and Magnus holders, facilitating easy assembly and operational modularity. It efficiently integrates into both existing and new production lines, optimizing throughput while maintaining product integrity, making it ideal for high-stakes environments like pharmaceutical manufacturing.
Engineered for minimal downtime, the system supports rapid changeovers with its quick-load mechanism, reducing lead times. Utilizing durable materials, it withstands the rigors of repeated use, ensuring long-term performance and compliance with stringent industry standards.
Additionally, the Viresolve®Pro addresses energy efficiency, reducing operational costs through optimized motor control, while its CIP-ready (Clean In Place) design allows for straightforward maintenance, promoting seamless operations in varied bioprocessing scenarios.
Benefits
- Ensures high viral safety standards with reliable filtration, protecting critical product pathways.
- Offers scalable solutions from pilot to large-scale production, meeting diverse processing needs.
- Reduces operational costs with energy-efficient design and optimized motor control.
- Simplifies maintenance with CIP-ready features, minimizing contamination risk.
- Seamlessly integrates with existing systems for enhanced productivity and reduced changeover times.
- Applications
- Molecular biology,Protein biology,Biopharmaceuticals,Mabs,Virus inactivation,Downstream processing,Mrna development,Pharmaceuticals
- End products
- Downstream bioprocessing solutions,Biopharmaceutical formulations,Monoclonal antibodies,Viral inactivated blood products,Mrna vaccines,Recombinant proteins,Viral vector vaccines,Therapeutic proteins
- Steps before
- Chromatography,Chemical Treatment
- Steps after
- Sterilization,Packing
- Input ingredients
- biologics feed streams,downstream mAb process,pre-filter feed,Pod filters,process scale feed
- Output ingredients
- filtered biologics,virus-free product,virus-retentive filtrate,pre-filtered solution
- Market info
- Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.
- Filtration system
- Viresolve®Pro/Pro+ Magnus Holders
- Filtration type
- Virus filtration
- Loading and unloading
- Quick and easy
- Holder footprint
- Minimized with vertical orientation
- Hydraulics
- Simple manual
- Process scale
- Up to 30 Pod filters
- Scalability
- 6x within the same footprint
- Construction
- Robust and easy to use
- Installation
- Easy setup of hardware
- Flow path
- Optimized single-use
- Adaptability
- Maximum with single-use flow paths
- Processing efficiency
- High
- Retention assurance
- Highest levels
- Product contact
- None
- Automation level
- Manual / PLC
- Batch vs. continuous operation
- Batch / Inline Continuous
- Cleaning method
- CIP / Manual
- Changeover time
- Quick and easy loading and unloading
- Scalability
- 6x scalability within the same footprint
- Setup time
- Fast setup of hardware
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compact footprint
- Minimized holder footprint with vertical orientation
- Loading and unloading
- Quick and easy loading and unloading
- Holder size
- Multiple lengths for various sized installations
- Holder design
- Robust construction with modular format
- Hydraulics
- Simple manual hydraulics
- Filter Holder Compatibility
- Viresolve®Pro Magnus,Viresolve®Pro+ Magnus
- Modular Design
- Yes,allows scalable configuration
- Loading/Unloading Process
- Quick and easy
- Integration with Prefilter
- Pod filter holder required
- Orientation and Footprint
- Vertical,minimized footprint
- Flow Path Adaptability
- Single-use,adaptable to changing needs
- Operational Scalability
- Pilot to process scale