Single-use fermentor for microbial fermentation
Enhance your microbial fermentation processes with a system designed for precise temperature control and efficient mixing, tailored for scalability from pilot to production stages.
Enhances Fermentation and Temperature Control
The HyPerforma™ Enhanced Single-Use Fermentor from Thermo Fisher Scientific integrates enhanced functionality into your microbial fermentation processes. With a 35% increase in jacketed surface area, this fermentor significantly optimizes temperature control by at least 21%. The proprietary mixing system, featuring three re-designed turbine impellers and a sparger configuration, ensures optimal sterility and mixing efficiency. Suitable for biopharmaceuticals and fine chemicals, it supports the production of monoclonal antibodies, insulin, and bioethanol. Operating with a 5:1 turndown ratio, it accommodates volumes as low as 60-L, ideal for batch and fed-batch operations. The fermentor is PLC-controlled for precise automation, ensuring seamless integration into existing production lines. Enhanced cable/tubing management and a minimized vessel footprint simplify installation and operation. Constructed from stainless steel, it offers robust chemical resistance, while the state-of-the-art foam sensor prevents exhaust filter failures, reducing downtime and maintenance.
Benefits
- Enhances productivity with precise temperature control and efficient heat transfer.
- Lowers operational costs through minimized downtime and maintenance requirements.
- Improves product yield with optimized mixing and sterility.
- Facilitates flexible production with scalable turndown ratios.
- Integrates seamlessly into production lines with reduced equipment footprint.
- Applications
- Fine chemicals, Nutraceuticals, Biopharmaceuticals, Enzymes, Biofuel
- End products
- Lipase enzymes, Bioethanol, Insulin, Monoclonal antibodies, Dietary supplements
- Steps before
- Media preparation, Inoculum development, Substrate preparation
- Steps after
- Harvesting, Downstream processing, Purification
- Input ingredients
- microbial cultures, Pichia, Bacillus, batch cultures, fed-batch cultures
- Output ingredients
- enhanced single-use fermentation, optimum cell viability, production scalability, fermentation products
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Capacity
- 300 L
- Jacketed Tank
- Yes
- Voltage
- 220/240 V
- Turndown Ratio
- 5
- Height-to-Diameter Ratio
- 3
- Enhanced Surface Area
- 35% increase
- Temperature Control Improvement
- 21%
- Working Volume
- Minimum 60 L
- Material
- Stainless Steel
- Mixing System
- Overhead
- Batch vs. continuous operation
- Batch / Inline Continuous
- Automation level
- Manual / PLC / SCADA
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Cleaning method
- CIP / Manual
- Temperature control capability
- Improved by 21%
- Footprint
- Minimized
- Working volume
- 60-L to 300-L
- Mixing system
- Overhead mixing
- Biological compatibility
- Yes
- Cleanability
- Yes
- Corrosive resistance (e.g. acids)
- Yes
- Microbial Cultures
- Pichia, Bacillus
- Tank capacity
- 300 L
- Tank shape
- Stirred-tank
- Footprint
- Minimized vessel footprint
- Jacket type
- Enhanced jacketed
- Vessel Height-to-Diameter Ratio
- 3
- Baffle inclusion
- Yes
- Impeller location
- Top-driven
- Access door
- Front access
- Mixing system type
- Unique proprietary overhead
- Bag loading
- Simplified with front access door
- Cable/tubing management
- Enhanced organization