Mini batch blender for pharmaceutical solids
In the pharmaceutical industry, manufacturing of low dosage, highly potent products poses significant challenges. Achieving minimal batch sizes without compromising on mixing homogeneity is essential for both early phase development and full-scale production.
Combine batch and continuous manufacturing processes
The Mini Batch Blender GBM 10 P by Gericke is designed to blend for continuous manufacturing of solids. It offers a semi-continuous approach, bridging the advantages of traditional batch processes with those of continuous manufacturing. The system allows for minimal batch sizes, ranging from less than 1 kg to 3 kg, and accommodates production rates of 0 to 20 kg/h without requiring scale-up. This flexibility makes it suitable for low dosage, highly potent products. The blender is equipped with advanced features like high containment and Wash-in-Place (WIP) capabilities, ensuring minimal operator exposure and easier cleaning processes. Suitable for integrating Process Analytical Technology (PAT), the system is designed for simple feeder startup and material tracking without the need for Residence Time Distribution (RTD) modeling.
Benefits
- Maximal mixing homogeneity even with very low API concentrations
- Handles minimal batch sizes of less than 1 kg to 3 kg
- Supports production rates of 0 to 20 kg/h without scale-up
- High containment and Wash-in-Place (WIP) capabilities
- Simple integration of Process Analytical Technology (PAT)