Glass bioreactor for cell culture processes
Optimize your cell culture and fermentation processes with a high-efficiency bioreactor designed to maximize mixing while minimizing shear, ensuring rapid temperature regulation for sensitive biomanufacturing operations.
Cultivates and Ferments Biopharmaceutical Products
The HyPerforma Glass Bioreactor from Thermo Scientific is a versatile solution designed for the complex demands of biopharmaceutical production. Featuring a borosilicate glass body and 316L stainless steel components, it provides excellent chemical resistance and durability. This bioreactor excels in cultivating and fermenting cells to produce high-value end-products like monoclonal antibodies, recombinant proteins, and more. The unique design employs a CFD-optimized impeller system for superior mixing efficiency while minimizing shear stress, thereby protecting delicate cell lines. With capabilities to efficiently heat and cool, the bioreactor supports both mammalian and microbial fermentation processes. Its bidirectional control system adapts seamlessly to a range of production requirements, from pilot to full-scale cGMP operations. Additionally, the ergonomic headplate allows for rapid setup, minimizing downtime between runs. Fully compliant with industry standards, it is an ideal choice for CDMOs and biotech manufacturers seeking precision and reliability in their production lines.
Benefits
- Enhances production efficiency with optimized mixing that preserves cell integrity.
- Improves thermal management using an advanced cooling loop for precise temperature control.
- Adapts to diverse bioprocessing needs with bidirectional system controls for flexible application use.
- Facilitates quick changeovers and minimal downtime through easy assembly and disassembly.
- Ensures compliance with industry regulations, supporting robust biopharmaceutical production standards.
- Applications
- Biopharmaceuticals,Cell culture processes,Fermentation processes
- End products
- Biologics,Viral vectors,Therapeutic cells,Monoclonal antibodies,Antibiotics,Organic acids,Enzymes,Vaccine substrates,Recombinant proteins,Probiotics
- Steps before
- Media Preparation,Sterilization,Cell Line Development
- Steps after
- Harvesting,Purification,Filtration
- Input ingredients
- suspension cell culture,adherent cell culture,mammalian applications,fermentation processes
- Output ingredients
- higher average kLa,completed cell culture processes
- Market info
- Thermo Fisher Scientific is renowned for providing innovative scientific instruments, laboratory equipment, and engineered-to-order solutions across various industries, esteemed for their high-quality products and expertise in life sciences, pharmaceuticals, and biotechnology sectors.
- Material
- Borosilicate Glass,Stainless Steel (316L),Silicone
- Height (Metric)
- 463.5 mm
- Height (English)
- 18.3 in.
- Width (Metric)
- 680 mm
- Width (English)
- 26.8 in.
- Max. Voltage
- 240 V
- Weight
- 23.0 kg
- Cooling System
- Cooling loop for thermal surface increase
- Mixing
- Impellers designed for maximum mixing with minimum shear force
- Cooling Rate
- Twice better than competitor products
- Control Type
- Bidirectional
- Working Mechanism
- Impeller-based mixing
- Integrated Steps
- Cooling loop in place of cold finger
- CIP/SIP
- CIP capable
- Batch vs. Inline Operation
- Batch
- Automation Level
- Bidirectional control
- Changeover Time
- Rapid assembly and disassembly
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Material
- Borosilicate Glass,Stainless Steel (316L),Silicone
- Dimensions
- Height
- Weight
- 23.0 kg
- Voltage
- Max. Voltage
- Integration possibilities
- Bidirectional control
- Assembly method
- Rapid assembly with coupling windows
- Motor adapter
- Coupling windows and alignment marker
- Head plate design
- Ergonomic for easy assembly/disassembly
- Thermal management
- Cooling loop for enhanced thermal surface