96-channel ultra high throughput protein analysis
Accelerate your research and development with simultaneous high-throughput analysis of proteins, antibodies, and peptides, enabling rapid characterization and streamlined workflows without microfluidics, ensuring increased accuracy and reduced operational costs.
Performs Rapid Quantitation and Binding Analysis
The Octet® RH96 from Sartorius is a cutting-edge biolayer interferometry system designed for high throughput analysis in pharmaceutical and biotech laboratories. This equipment excels in conducting rapid quantitation and binding experiments, using a microfluidics-free Dip and Read technology that minimizes maintenance while maximizing uptime. It is ideal for applications involving monoclonal antibodies, therapeutic proteins, and other biologic therapies, making it a crucial asset for biopharmaceutical development and research. The system can process up to 96 samples simultaneously, offering unparalleled speed and flexibility in assay automation and integration. Compatibility with standard 96- and 384-well plates allows for scalability and high processing capacity, crucial for time-sensitive R&D environments. With robotic compatibility, the Octet® RH96 facilitates seamless automation, reducing manual input and potential for human error. Its robust design and compliance with industry standards ensure reliable performance in demanding operational settings, while Sartorius provides comprehensive engineering support for custom configurations and integration into existing workflows.
Benefits
- Expedites drug development with high throughput analysis, minimizing assay completion time.
- Enhances data reliability with microfluidics-free operation, reducing maintenance and operational costs.
- Facilitates seamless integration and scalability with automation and robotic compatibility.
- Boosts productivity by simplifying workflow through automation-ready design, minimizing manual intervention.
- Ensures industry compliance, supporting GMP standards for pharmaceutical manufacturing.
- Applications
- Cell culture supernatants,Proteins,Crude cell lysates,Antibodies,Biopharmaceuticals,Virus-like particles,Peptides
- End products
- Viral vaccines,Peptide-based drugs,Biologic therapies,Monoclonal antibodies,Cell culture-derived therapeutics,Diagnostic reagents,Therapeutic proteins
- Steps before
- Sample Preparation,Cell Culture,Protein Expression,Buffer Preparation
- Steps after
- Data Analysis,Quality Control,Protein Contaminant Testing,Report Generation
- Input ingredients
- protein samples,antibodies,peptides,serum containing media,DMSO buffers,virus-like particles,cell culture supernatants,crude cell lysates
- Output ingredients
- sensorgrams,epitope binning matrices,kinetic data,concentration data,binding rates,IgG quantitation,epitope binning analysis
- Market info
- Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.
- Sample Volume
- 40–80 μL/well (384-well tilted bottom microplate),180–220 μL/well (96-well microplate)
- Analysis Temperature
- Ambient + 4°C to 40°C,in 1°C increments
- Simultaneous Read Capacity
- 8,16,32,48,or 96 wells
- Quantitation Range
- 32–96 biosensors
- 1.0–700 μg/mL at 400 rpm
- Dissociation Rate Constant (kd)
- 10^-6 to 10^-1 s^-1
- Association Rate Constant (ka)
- 10^1 to 10^7 M^-1s^-1
- Affinity Constant (KD)
- 1 mM – 10 pM
- Baseline Noise (RMS)
- < 3 pm (8–16 biosensors)
- < 8 pm (32–96 biosensors)
- Baseline Drift
- < 0.1 nm/hour
- Detection Type
- Label-free,Dip and Read format
- Weight
- 200 lbs (90.7 kg)
- Dimensions
- 30.1 in x 31.5 in x 31.5 in (77 cm x 80 cm x 80 cm)
- Molecular Weight Detection
- >150 Da (8–16 biosensors),>5000 Da (32–96 biosensors)
- Automation
- Robot compatible microplate and biosensor tray loading
- Automation level
- Automation-ready and robot-compatible
- Batch vs. continuous operation
- Batch (96-well plate)
- Cleaning method
- Microfluidics-free Dip and Read
- Energy efficiency
- State-of-the-art high throughput
- Changeover time
- Streamlined workflows with automation
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Footprint
- 30.1 in x 31.5 in x 31.5 in (77 cm x 80 cm x 80 cm)
- Weight
- 200 lbs (90.7 kg)
- Sample Type Compatibility
- Proteins,antibodies,peptides,serum containing media,DMSO containing buffers,virus-like particles,untreated cell culture supernatants and crude cell lysates
- Sample Plate
- Standard,96-well and 384-well,black,tilted bottom microplates
- Molecular Weight Detection
- >150 Da (8–16 biosensors),>5000 Da (32–96 biosensors)
- Control panel type
- Automation-ready,robot-compatible
- Integration possibilities
- Microplate and biosensor tray loading