Surface plasmon resonance (spr) sensor chips
Enhance your molecule interactions analysis with precise sensor technology that delivers high sensitivity and rapid data acquisition, critical for drug discovery and biopharmaceutical research.
Analyzes Biomolecular Interactions Efficiently
The Octet® SF3 SPR System by Sartorius is designed to revolutionize the analysis of biomolecular interactions with precision and speed. Utilizing Surface Plasmon Resonance, it provides exceptional sensitivity for detecting small and large molecules in complex mixtures. Key features include novel OneStep® and NeXtStep™ gradient injection technologies, enabling high-quality kinetics and affinity data collection. This system is indispensable for applications across pharmaceuticals, biologics, vaccines, and regenerative medicine, facilitating the production of recombinant proteins, therapeutic antibodies, and mRNA vaccines. With its capacity to accommodate varying sample volumes and types, the Octet® SF3 seamlessly integrates into high throughput and batch operations. It is automation-ready, ensuring scalability and cost-efficiency in a production line. The system’s robust construction is enhanced by automated cleaning protocols, supporting long-term use and compliance with industry standards, making it an ideal solution for research and manufacturing environments.
Benefits
- Enhances data accuracy and reproducibility for critical research and production phases.
- Supports diverse applications, from mRNA vaccines to therapeutic antibodies, expanding your operational capabilities.
- Streamlines integration with existing systems, maximizing throughput without extensive downtime.
- Reduces labor costs through automated cleaning and maintenance protocols.
- Compliant with industry standards to ensure regulatory requirements are met.
- Applications
- Biologics,Immuno-oncology,Vaccines,Functional profiling,Nutraceuticals,Cytokines,Monoclonal antibodies,Mrna production,Biosimilars,Regenerative medicine,Bioconjugation,Biopharmaceuticals,Research growth factors,Blood and plasma,Cell and gene therapy,Antibody discovery
- End products
- Oncolytic viruses,Erythropoietin,Plasma-derived coagulation factors,Insulin,Nutraceutical capsules,Car-t cell products,Covid-19 vaccines,Therapeutic antibodies,Peptide hormones,Bispecific antibodies,Interleukins,Mrna vaccines,Hemophilia treatments,Cancer immunotherapies,Growth hormone therapy,Interferons,Antibody-drug conjugates,Recombinant proteins
- Steps before
- Sample Preparation,Cell Culture,Media Preparation,Reagent Preparation
- Steps after
- Data Analysis,Kinetics Determination,Affinity Analysis,Result Interpretation
- Input ingredients
- large molecules,molecular complexes,viruses,whole cells,small molecules,antibody fragments,samples,reagents,proteins,organic molecules,ligands,analyte complexes
- Output ingredients
- robust results,reproducible results,kinetics data,affinity data,interaction analysis,high-quality data,documented evidence of performance,analyte capture
- Market info
- Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.
- Sensitivity
- Exceptional for small and large molecules
- Baseline noise
- Low
- Injection volumes
- Large
- Kinetic analysis
- High-quality kinetics and affinity data
- Matrix length from gold surface
- 2 nm,50 nm,150 nm
- Binding capacity
- Low to high
- Bond type
- Covalent bond with ligand
- Analyte type
- Small molecules,large molecules,viruses,proteins
- Sensor chip type
- COOH1,PCH,CDL,CDH,SADH,HisCap
- Sensitivity
- Low baseline noise and drift
- Injection Modes
- OneStep® and NeXtStep™ Gradient Injection Technologies
- Data Accuracy
- High-quality kinetics and affinity data
- Operational Qualification
- Documented evidence of platform performance
- Maintenance Protocols
- Cleaning,desorb,and decontamination protocols
- Automation level
- Automatically generates robust and reproducible results
- Batch vs. continuous operation
- Batch
- Cleaning Method
- Weekly cleaning using Maintenance Kit
- Chip Binding Capacity
- Varies with matrix type (low,medium,high)
- Binding Matrix Type
- COOH1,PCH,CDL,CDH,and HisCap
- Immobilization Matrix Classification
- Classified by its immobilization matrix,binding capacity or type of bond
- Matrix length from gold surface
- ~2 nm
- Matrix length from gold surface
- 50 nm
- Matrix length from gold surface
- 150 nm
- Control Panel Type
- Touchscreen / Button-based
- Sensor Chip Compatibility
- COOH1 / PCH / CDL / CDH / SADH / HisCap
- Injection Mode
- OneStep® / NeXtStep™ Gradient Injection
- Sample and Reagent Vial Sizes
- 0.9 mL / 2 mL / 7.5 mL
- Sample Rack Adapter Type
- 96-well / 384-well