Syringe filling line for parenteral drugs
Ensure precise dosage and sterility with this high-speed syringe filling line, ideal for handling highly potent parenteral drugs and biopharmaceuticals with minimal contamination risk.
Fills and Seals Pre-Filled Syringes
The Syringe Filling Machines from Syntegon streamline your production line, integrating automation to handle sophisticated processes such as de-nesting, filling, closing, and inspection. Specializing in high-value biopharmaceuticals and parenteral drugs, these machines ensure precision in both liquid and lyophilized forms. Capable of high-speed and continuous operation, they maintain sterility by minimizing operator intervention, using PLC-controlled technology for seamless integration into existing systems. Available with options for barrier systems and aseptic transfer, the machines support compliance with GMP standards, providing safe handling for injectable hormones and recombinant proteins. Equipped with automatic clean-in-place (CIP) systems, maintenance is simplified, ensuring reliable operation with minimal downtime. Custom configurations are available to suit specific manufacturing needs, backed by engineering support for optimal integration.
Benefits
- Enhances product safety and precision with fully automated, aseptic processing.
- Increases production efficiency with high-speed operations for both small and large batches.
- Ensures sterility and minimizes contamination risk through barrier systems and CIP.
- Reduces labor costs with integrated PLC-controlled systems and minimal operator intervention.
- Customizable configurations support diverse pharmaceutical and biopharmaceutical applications.
- Applications
- Parenteral drugs,Biopharmaceuticals,Lyophilized pharmaceuticals,Liquid pharmaceuticals
- End products
- Lyophilized chemotherapy drugs,Insulin,Monoclonal antibodies,Blood clotting factors,Biologics concentrates,Anticancer therapies,Antiviral injections,Vaccine solutions,Injectable hormones,Recombinant proteins
- Steps before
- De-nesting,Sterile packaging transfer,Bag and tub opening
- Steps after
- Rod insertion,Labeling,Inspection,Sterilization,Re-nesting
- Input ingredients
- pre-filled syringes,parenteral drugs,nested syringes,containers,sterile packaging,ready-to-use syringes,bulk syringes
- Output ingredients
- filled syringes,sealed syringes,labeled syringes,inspected syringes,sterilized containers
- Market info
- Syntegon is known for its expertise in processing and packaging technology, offering innovative solutions for the food and pharmaceutical industries. It has a strong reputation for advanced equipment, sustainability, and customer-oriented service.
- Automation
- Fully automated
- Filling speed
- Up to 36,000 units/h
- Filling volume
- Diverse sizes
- Accuracy
- In-process control (IPC)
- Handling capacity
- Up to 400 syringes per minute
- Inspection speed
- High-speed inspection
- Container handling
- Pre-filled syringes,cartridges,vials
- Sterilization process
- Vacuum-steam,steam/air mixture,hot water shower
- Energy efficiency
- Optimized energy requirements
- Product handling
- Gentle and secure processing
- Automation level
- Fully automated
- Batch vs. continuous operation
- Batch and Continuous
- CIP/SIP
- Automatic CIP
- Cleaning method
- Aseptic cleaning
- Energy efficiency
- Optimized for SVP/LVP
- Filling process
- In-process control (IPC)
- Product handling
- Gentle removal from nest
- Sterility assurance
- RABS or Isolator
- Inspection integration
- Inline inspection included
- Nesting and de-nesting
- Automatic de-nesting and re-nesting
- Transfer method
- Automated RTU Handling
- System flexibility
- Modular setup
- Process monitoring
- Continuous
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Handling of toxic substances
- OEB5
- Footprint
- Adaptable to room conditions and floor plans
- Machine Configuration
- Modular set-ups
- Compact Design
- Compact and clean design for labeling machines
- Handling Units
- Dedicated handling units for precise syringe removal
- Inline Inspection
- Integrated with specific inspection tasks
- Gripper/Pusher Technology
- For careful syringe removal and placing
- Camera-based Identification
- For tub description recognition
- Discharge Method
- Rod insertion and labeling in a single platform
- Control panel type
- HMI / Touchscreen
- Integration possibilities
- SCADA / MES compatible
- Barrier system integration
- RABS / Isolator
- Machine configuration
- Single pack / Combi line
- Output customization
- Small to high output