Bench-top syringe & cartridge closing system
In small-batch pharmaceutical manufacturing, precise and consistent closing of syringes and cartridges is critical to ensure product integrity and compliance with regulatory standards.

Accurate syringe and cartridge closing with process flexibility
The Container Closing System (CCS) by AST is a benchtop, semi-automatic unit designed for accurate and repeatable closing of syringes and cartridges. It employs both vacuum and vent-tube methods, optimized for different container sizes with minimal format part changes. This system’s electronic controls allow precise piston insertion, making it suitable for applications needing high control and flexibility, such as biologics manufacturing, clinical trial materials, and stability studies. The compact, aseptic design conforms with cGMP standards, ensuring compatibility with cleanrooms, bio-safety cabinets, laminar airflow hoods, and isolators. Additional features include intuitive HMI touchscreen controls, multi-stage vacuum insertion, and optional Electronic Batch Reporting (EBR) for documentation and compliance.
Benefits
- Precise and repeatable piston placement
- Intuitive process control with HMI touchscreen
- Process flexibility for various container sizes
- Compact design compatible with aseptic environments
- Optional Electronic Batch Reporting for compliance