Bench-top syringe & cartridge closing system

Closes Syringes and Cartridges Precisely

The Container Closing System (CCS) from AST is a benchtop, semi-automatic machine designed to provide precise control over the syringe and cartridge closing process. This system stands out for its use of both vacuum and vent-tube methods, accommodating a range of container sizes with minimal format changes. Ideal for biologics, vaccines, and personalized medicine, the CCS ensures contamination-free sealings, such as those required for monoclonal antibodies and mRNA vaccines.

Operating under aseptic conditions, the system supports small-batch production with its compact footprint, making it suitable for laboratory and cleanroom environments. Key applications include clinical trial materials manufacturing, compounding pharmacies, and processing cell and gene therapies. The electronic control system offers intuitive operation via an HMI touchscreen, allowing operators to create and monitor precise insertion recipes.

Featuring AST’s patented multi-stage vacuum insertion process, the CCS guarantees consistent piston placement, essential for biologic and compounded pharmaceutical products sensitive to oxidation. An optional Electronic Batch Reporting (EBR) system enhances batch documentation, regulatory compliance, and technology transfer. Constructed from pharmaceutical-grade stainless steel, the system also offers compatibility upgrades for isolator use, ensuring compliance with GMP standards.