Aseptic filling system for biopharmaceutical products
This system ensures sterility in high-volume aseptic filling operations, streamlining single-use assembly changeovers for efficient drug manufacturing and eliminating cross-contamination risks.
Sterile Aseptic Filling and Fluid Path Management
The AccuFill™ Aseptic Filling System from Meissner Corporation specializes in revolutionizing biopharmaceutical and pharmaceutical manufacturing with its single-use design that eliminates cross contamination and reduces cleaning requirements. This system is ideal for aseptic filling of vaccines, monoclonal antibodies, and parenteral drugs, using proprietary disposable fill liners that seamlessly integrate into sterile filling processes. Designed for capacities ranging from 100 L to 20,000 L, it supports swift batch changeovers to minimize downtime. Featuring robust automation, it offers efficient fluid path management, enhancing the throughput of single-use assemblies. Built to comply with stringent biopharmaceutical standards, it ensures reliable and sterile production environments without extensive manual intervention. The system is customizable for unique operational needs and supports easy scalability of biopharmaceutical operations.
Benefits
- Minimizes cross contamination risks with single-use components.
- Enhances operational efficiency with quick batch changeovers.
- Lowers cleaning and validation costs with disposable fill liners.
- Optimizes throughput for large volume aseptic applications.
- Aligns with biopharmaceutical compliance standards, ensuring product integrity.
- Applications
- Drug manufacturing,Fill and finish segment,Biopharmaceuticals,Single-use assemblies,Sterile fill/finish,Aseptic filling,Pharmaceuticals
- End products
- Parenteral drugs,Vaccines,Lyophilized drugs,Monoclonal antibodies,Injectable biologics,Aseptic iv solutions,Cell culture media bags,Pre-filled syringes,Sterile drug vials,Single-use bioprocess containers
- Steps before
- Purification,Mixing,Hydration
- Steps after
- Sterilization,Packing,Quality Control
- Input ingredients
- biopharmaceutical products,single-use fluid path,fill liner,biocontainers,extended fill tubing section
- Output ingredients
- sterile filled biopharmaceutical products,filled single-use assemblies
- Market info
- Meissner is known for manufacturing advanced filtration and single-use systems for biopharmaceutical, pharmaceutical, and other critical industries, renowned for its innovation and high-quality, reliable solutions supporting complex manufacturing processes.
- Automation
- Automated with PLC-controlled system
- Filling capacity
- 1 L to 20,000 L
- Changeover time
- Minimal downtime with quick changeover
- Compatibility
- Single-use assemblies
- Filling accuracy
- ±0.5%
- Filling speed
- Up to 50 fills/min
- Batch size
- 100 L to 20,000 L
- Material
- Proprietary disposable fill system liners
- Cross-contamination prevention
- Fully disposable system
- Cleaning method
- No cleaning required due to disposable components
- Batch size
- 100 L to 20,000 L
- Batch vs. continuous operation
- Batch
- Changeover time
- Minimal downtime
- CIP/SIP
- Single-use reduces cleaning
- Automation level
- Semi-automated / Automated
- Cleaning method
- Disposable single-use liners
- Air incorporation control
- Integrated
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Filling purpose
- Aseptic filling
- Container type
- Single-use assemblies
- Container size
- 1 L – 20 L
- Control panel type
- PLC
- Single-use options
- Yes
- Integration possibilities
- With existing systems
- Batch size customization
- 100 L to 20,000 L