Wave-mixed bioreactor for shear-sensitive cell cultures

Create stable, gentle environments for cell cultures

The Biostat® RM from Sartorius is a GMP-compliant wave-mixed bioreactor system designed to handle sensitive cell lines effectively. This system utilizes a rocking motion to create wave-induced mixing, avoiding submerged gassing or stirrer elements, making it ideal for shear-stress-sensitive cell cultures. The Biostat® RM is paired with single-use Flexsafe® RM bags, which offer various configurations like basic, optical, and perfusion. These bags ensure sterile cultivation and precise control of pH, dissolved oxygen, and biomass. Available in working volumes ranging from 0.1 to 100 L, the modular design of the Biostat® RM facilitates easy scale-up from development to commercial manufacturing. It is powered by the Biobrain® automation platform, which provides advanced process control and seamless integration with existing systems. Suitable for applications in regenerative medicine, vaccine production, and monoclonal antibody manufacturing, the Biostat® RM offers flexibility and ease of use for various biopharma processes.