Continuous flow hydrogenation reactor for corrosive reagents
Transform your hydrogenation processes with a reactor engineered for exceptional chemical resistance, enabling safe and efficient handling of corrosive reagents without the need for hydrogen cylinders.
Generates and Mixes Hydrogen for Flow Reactions
The H-Cube® Pro Hastelloy from ThalesNano is a continuous flow hydrogenation reactor designed for researchers and manufacturers in the pharmaceutical and fine chemical industries. This reactor stands out for its on-demand hydrogen generation from water via electrolysis, eliminating the need for external hydrogen cylinders. Its unique design features Hastelloy C wetted parts, providing superior chemical resistance essential for handling corrosive reagents like mineral acids and bases, as well as oxidizing agents.
Operating within a temperature range of 10 to 150°C and a pressure range up to 100 bar, the H-Cube® Pro Hastelloy efficiently manages hydrogenation processes with fine control over reaction conditions such as pressure, temperature, and flow rate. The integrated microHPLC pump ensures accurate solvent delivery, which, when mixed with hydrogen, supports a stable reaction environment.
Ideal for producing active pharmaceutical ingredients, custom fine chemical compounds, and specialty polymers, this reactor accommodates reactions with variable scales from milligrams to grams. Its pre-packed CatCart® columns simplify catalyst handling, enhancing throughput and reducing downtime. Suitable for bench-top operations, this equipment is a versatile solution for R&D and processing departments seeking reliable performance in complex hydrogenation applications.
Benefits
- Enhances safety and convenience by generating hydrogen on demand, eliminating cylinder handling.
- Provides excellent chemical resistance, allowing work with aggressive reagents without equipment degradation.
- Increases productivity with precise reaction control and high throughput in continuous operations.
- Simplifies catalyst management and reduces maintenance time with pre-filled CatCart® columns.
- Adapts to diverse reaction needs with a flexible temperature and pressure range.
- Applications
- Specialty chemicals,Fine chemicals,Petrochemicals,Catalysts,Pharmaceuticals
- End products
- Custom fine chemical compounds,Active pharmaceutical ingredients,Specialty oxidized organic compounds,Catalytically modified polymers,Hydrotreating catalysts
- Steps before
- Reagent preparation,Solution mixing,Reactant solution preparation,Solvent preparation
- Steps after
- Product collection,Product purification,Post-reaction analysis,Solution separation
- Input ingredients
- corrosive reagents,mineral acids,bases,strong oxidizers,ferric chlorides,cupric chlorides,nitric acid,formic acid,acetic acid,acetic anhydride,wet chlorine,sea water,brine solutions,hypochlorite solutions,chlorine dioxide solutions
- Output ingredients
- reaction mixture,product in collection vial
- Market info
- Thalesnano is known for manufacturing advanced flow chemistry solutions, particularly in catalyst and hydrogenation technologies. They are recognized for their expertise in continuous processes, enhancing safety and efficiency in chemical synthesis.
- Temperature range
- 10 to 150°C
- Pressure range
- Atmospheric pressure to 100 bar
- Liquid flow rate
- 0.1 – 3 mL/min
- Optimal liquid flow rates
- 0.5 – 2 mL/min
- Maximum hydrogen production rate
- 60 Nml/min (in 100% Bub. Det. Mode)
- Dimensions
- Height
- Width
- 37 cm
- Depth
- 51 cm
- Weight
- 23 kg (46.3 lbs)
- Power requirements
- 115-230 VAC
- 5A/115 VAC
- 2.5A/230 VAC
- 47-63 Hz,300 W
- Water reservoir capacity
- 300 mL
- Working mechanism
- Continuous flow hydrogenation
- Hydrogen generation
- On-demand from water
- Temperature range
- 10-150°C
- Pressure range
- Atmospheric to 100 bar
- Flow control
- PLC-controlled
- Scale of reactions
- Milligrams to grams
- Corrosive reagent handling
- Utilizes Hastelloy for chemical resistance
- Hydrogen source
- Electrolysis of water
- Catalyst management
- Pre-filled CatCarts®,no manual handling
- Process type
- Continuous flow
- Corrosive resistance (e.g. acids)
- Yes,compatible with mineral acids and bases,strong oxidizers
- Cleanability
- Yes,designed for easy use without catalyst handling
- Density/particle size
- Applicable to a range of particle sizes in CatCarts
- Use of heterogenous catalysts
- CatCarts®
- Handling of corrosive reagents
- Ferric and cupric chlorides,mineral acids
- Machine footprint
- Width
- Weight
- 23 kg (46.3 lbs)
- Material of construction
- Hastelloy C
- Water reservoir capacity
- 300 mL
- Discharge method
- Collection vial
- Control panel type
- Touch screen
- Control panel type
- Touch screen interface
- Compact footprint
- Yes