Biological fermentation tank for pharmaceutical production

Ensure consistent high-yield biological culture results with reliable, scalable fermentation tanks, ideal for applications requiring optimal oxygenation and precise environmental control, such as when cultivating E. coli and producing life-saving vaccines.

Cultivates and Ferments Microbial Cultures

AUSTAR’s Biological Fermentation Tank offers a robust solution for scaling biopharmaceutical production from research to commercial operations. This tank is engineered for precision microbial cultivation and fermentation, accommodating volumes from 5 to 30 kiloliters, and is ideal for producing biological drugs, including insulin, HPV vaccines, and pneumococcal vaccines.

The fermentation process is controlled with state-of-the-art automation technologies, ensuring optimal conditions for high oxygen-consuming bacteria such as E. coli and Pichia pastoris cultures. Built to comply with GMP regulations and ASME-BPE standards, the tank guarantees safety and reliability in demanding pharmaceutical environments.

The equipment’s modular design facilitates seamless integration into existing production lines, with configurable options available for tailoring to specific needs. AUSTAR provides comprehensive engineering support, ensuring each tank meets precise operational requirements. Constructed from materials adhering to ASME-U, GB150, and PED standards, the tank offers durable performance with excellent corrosion resistance, maintaining integrity over extensive use.

Cleaning is efficient and contamination-free, supporting compliance with stringent industry regulations. This versatility makes the AUSTAR Biological Fermentation Tank an indispensable asset for companies aiming to enhance their biomanufacturing processes.

Benefits

  • Supports scalable production, from R&D to commercial batches, enhancing operational flexibility.
  • Ensures high-yield microbial cultures with precise environmental control, boosting production efficiency.
  • Reduces compliance risks with GMP and ASME-BPE aligned design.
  • Minimizes contamination through seamless CIP integration, maintaining product quality.
  • Enhances equipment longevity and reliability with corrosion-resistant materials.

General


Applications
Vaccines,Microbial culture fermentation,Biopharmaceuticals,Recombinant protein drugs,Biological drugs
End products
E. coli cultures,Insulin,Hpv vaccine,Pneumococcal vaccine,Pichia pastoris cultures
Steps before
Laboratory research and development,Pilot scale production
Steps after
Commercial scale production,Quality measurement and analytics,Packging,Aseptic containment
Input ingredients
microbial culture,E. coli,Pichia pastoris
Output ingredients
recombinant protein drugs,insulin,vaccines,HPV vaccine,pneumococcal vaccine
Market info
Austar is known for specializing in the design and manufacture of engineered-to-order industrial equipment, particularly in the pharmaceutical and biotechnology sectors, offering solutions that focus on quality, innovation, and meeting specific customer requirements.

Technical Specifications


Volume Range
5–30 kiloliters
Compliance
GMP regulations,ASME-BPE,ASME-U,GB150,PED
Suitable for
High oxygen consuming bacteria like E. coli and Pichia pastoris
Application Scale
Laboratory R,D to pilot scale to commercial scale
Biological Drug Capability
Recombinant protein drugs (e.g.,insulin),vaccines (HPV,pneumococcal)
Customization
Customized engineering solutions available

Operating Characteristics


Batch vs. continuous operation
Batch
CIP/SIP
CIP 121°C / SIP 135°C
Automation level
PLC / SCADA
Cleaning method
CIP
Changeover time
Quick changeover

Product type Characteristics


Microorganism cultivation
E. coli / Pichia pastoris
Biological drugs
Recombinant protein / Vaccines

Physical Characteristics


Tank Volume
5–30 kiloliters

Custom Options


Modular design
Yes
Volume range
5–30 kiloliters
Pressure vessel standards
ASME-U,GB150,PED
Production scale adaptability
Laboratory,Pilot,Commercial
User-friendly design
Available