Industrial hydrogenation plant for pharmaceutical raw materials

Optimize your hydrogenation processes with a modular plant designed to enhance efficiency and flexibility, ensuring maximum yield and consistent quality for your complex chemical reactions.

Facilitates Hydrogenation for Diverse Chemical Processes

The EKATO Modular Hydrogenation Plant is designed to tackle complex hydrogenation challenges across pharmaceutical and chemical industries. What sets this system apart is its modular approach, allowing for versatile production configurations. Central to its design is the EKATO hydrogenation reactor, equipped with the combined gassing system for efficient gas-liquid reactions. Utilizing a two-zone dispersion for optimal mass transfer, this plant efficiently processes active pharmaceutical ingredients, sugar alcohols, and hydrogenated vegetable oils, among others.

With reactor volumes ranging from 50 to 6000 liters and design pressures up to 150 bar, the plant supports both batch and continuous operations. The plant features PLC automation for seamless production line integration and energy-saving technologies like self-aspirating gas turbines, which reduce operational costs. Fabricated with corrosion-resistant materials, these plants ensure long-term reliability and meet stringent regulatory standards, including GMP compliance. Cleanup and maintenance are streamlined through integrated CIP systems, providing quick cleaning turnaround and minimizing downtime.

Moreover, EKATO offers extensive customization options and engineering support, tailoring solutions to meet specific client requirements and ensuring optimal performance in diverse operational environments.

Benefits

  • Enhances production flexibility with modular design for quick adaptation to various processes.
  • Optimizes reaction efficiency with superior gas-liquid mixing, ensuring high product yield.
  • Saves on operational costs through integrated energy-efficient components like self-aspirating turbines.
  • Maintains rigorous safety and quality standards with GMP-compliant configurations.
  • Minimizes downtime with integrated CIP systems, ensuring swift and thorough cleaning.

General


Applications
Food,Sugar alcohols,Biofuels,Biotechnology,Fine chemicals,Fats,Sugars,Oils,Fatty acids,Plastics,Minerals,Basic chemicals,Batteries,Pharmaceuticals
End products
Hydrogenated vegetable oils,Peanut oil,Palmitic acid,Plastic precursors,Canola oil,Stearic acid,Hydrotreated vegetable oil (hvo),Aniline,Hydrotreated mineral oils,Triglycerides,Active pharmaceutical ingredients (apis),Biopolymers,Mannitol,Maltitol,Bioplastic intermediates,Battery electrode materials,Ethanol,Sorbitol,Toluene diisocyanate (tdi)
Steps before
Catalyst preparation,Reaction setup,Raw material preparation
Steps after
Filtration,Post-hydrogenation cooling,Product separation,Final packaging
Input ingredients
pharmaceutical raw materials,fine chemicals,specialty chemicals,sugars,fats,fatty acids,oils,basic chemicals,catalyst
Output ingredients
active pharmaceutical ingredients (API),sugar alcohols,hardened fats,chemical products
Market info
Ekato is renowned for its expertise in mixing technology and process engineering, providing innovative and high-quality solutions for industrial mixing processes across various sectors, including chemical, pharmaceutical, and cosmetics industries.

Technical Specifications


Useful volume
5 liters - 200 m3
Design pressure
up to 220 bar
Design temperature
150 to 400°C
Material
carbon steel,stainless steels,Ni-based materials,titanium
Heat transfer vessel wall
double shell or half pipe coils
Heat transfer internally
tube coils,tube bundle heat exchangers,plate heat exchangers
Reactor sizes
50 l to 6000 l usable volume
Design pressure (reactor module)
6 – 150 bar
Hygienic design
Prevents cross-contamination
Filling volume (pilot plant)
60 liters
Design temperature (pilot plant)
250°C
Design pressure (pilot plant)
100 barg
Pressure capability
up to 100 bar
Temperature capability
up to 250°C

Operating Characteristics


Batch vs. continuous operation
Batch / Inline Continuous
Automation level
Manual / PLC / SCADA
CIP/SIP
CIP 121°C / SIP 135°C
Cleaning method
CIP / Manual
Energy efficiency
0.5–2 kWh/kg moisture

Material Compatibility


Corrosive resistance (e.g.,acids)
Various metallic materials (carbon steel,stainless steels,Ni-based materials,titanium,etc.)
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Hydrogenation type
Batch or continuous

Physical Characteristics


Machine footprint
Compact design
Reactor size
50 l to 6000 l usable volume
Design pressure
6 – 150 bar
Design temperature
150 to 400°C
Material
Carbon steel,stainless steels,Ni-based materials,titanium
Heat transfer
Double shell or half pipe coils,tube coils,bundle heat exchangers
Discharge method
Bottom outlet valve
Insulation
Included
Control system
Outside the skid
Modular design
Yes (for plant extensions/conversions)
Skid-mounted
Yes

Custom Options


Control panel type
Integrated / Remote
Modular design
Yes
Customizable configuration
Able to suit client needs
Reactor sizes
50 L to 6000 L
Design pressure
6 – 150 bar
Material
Carbon steel / Stainless steel / Ni-based materials / Titanium
Reactor options
Batch / Continuous
Drive type
Mechanical seal / Magnetic drive
Safety features
Advanced safety mechanisms
Instrumentation
Available options for various needs