High shear wet granulation system

Experience efficient wet granulation with precise control over granule density and moisture content, ensuring unparalleled consistency and quality in your final product.

Processes Powders into Uniform Granules

The GMX-25 Granumeist from Freund is a high shear granulation mixer meticulously designed to enhance your wet granulation process. Its top-drive mechanism simplifies cleaning and maintenance, promoting user safety and efficiency. Highly adaptable, this system features user-defined mixer and chopper speeds, and an integrated peristaltic pump for precise liquid addition. Ideal for pharmaceutical manufacturers, it effectively processes powders into granules, perfect for tablets and supplements. The GMX-25’s flexible design includes both aqueous and solvent processing capabilities, with an optional jacketed bowl for temperature control. Mounted on casters for portability, it incorporates a vertical shaft chopper and tip cart for easy handling. Compliant with industry standards, it supports both automatic and manual operations, offering batch and pilot scalability. Its Smart-Safe™ containment and optional advanced COMPUTM automation ensure process validation and data integrity under 21 CFR Part 11 compliance.

Benefits

  • Enhances product consistency with precise granulation and mixing control.
  • Streamlines operations and minimizes cleaning time with top-drive and removable bowl design.
  • Improves product safety and quality with scalable process validation and data integrity.
  • Increases operational flexibility, handling both aqueous and solvent-based processes effectively.
  • Facilitates easy maneuverability and integration into existing production lines with its portable, self-contained system.

General


Applications
Supplements,Pharmaceutical tablets,Fine chemicals,Nutraceuticals,Coating materials,Pharmaceuticals
End products
Fine chemical granules,Coated pharmaceutical tablets,Nutraceutical powders,Vitamin supplements,Controlled-release tablets,Pharmaceutical granules
Steps before
Powder Preparation,Ingredient Blending
Steps after
Drying,Tablet Coating,Packaging
Input ingredients
powders,aqueous solutions,solvents
Output ingredients
medium density granules,high density granules
Market info
Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.

Technical Specifications


Bowl Capacity
25 L
Working Capacity
8.25 - 17 L
Mixer Speed
43 - 425 RPM
Automation
Automatic (Recipe Driven) and Manual Mode
Data,Recipe Handling System
21 CFR Part 11
Granulation Method
Wet Granulation
Blade Speeds
User-Defined
Solution Addition
Integrated Peristaltic Pump
Temperature Control
Optional Jacketed Bowl
Granulation Time
Multiple End Point Detection
Electrical and Compressed Air Connections
Mounted on Casters for Maneuverability
Data Collection
USB Data Collection Port

Operating Characteristics


Automation level
Automatic (Recipe Driven) and Manual Mode
Batch vs. continuous operation
Batch
CIP/SIP
Easy Cleaning and Maintenance
Cleaning method
Removable Bowl for Cleaning

Material Compatibility


Abrasion resistance
High
Biological compatibility
Yes
Cleanability
Easy to clean
Corrosive resistance (e.g. acids)
Moderate
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm


21 CFR Part 11
Data,Recipe Handling System
Smart-Safe™ Containment
Optional

Physical Characteristics


Machine Footprint
Portable,Self-Contained System
Bowl Capacity
25 L
Working Capacity
8.25 - 17 L
Discharge Method
Tip Cart for Quick Removal and Easy Discharge
Control Panel Type
Color Touchscreen Control System
Removable Bowl
For Superior Cleaning and Maintenance

Custom Options


Control panel type
Color Touchscreen Control System
Integration possibilities
USB Data Collection Port,COMPUTM Automated Control System
Portability
Mounted on Casters for Maneuverability
Cleaning and Maintenance
Removable Bowl for Superior Cleaning
Processing Modes
Automatic (Recipe Driven) and Manual Mode
Temperature Control
Optional Jacketed Bowl
End Point Detection Parameters
Mixer Power,Granulation Time