Vacuum tray dryer for pharmaceutical applications
Optimize drying of heat-sensitive compounds while maintaining product integrity with a vacuum tray dryer, ideal for precise moisture control in pharmaceutical production processes.
Dries and Contains Sensitive Pharmaceutical Compounds
The CakeStand™ Vacuum Tray Dryer from Powder Systems Limited (PSL) is designed to address the critical drying needs of the pharmaceutical and chemical industries. This equipment features a fully sealed vacuum chamber and direct heating shelves, ensuring uniform drying with validated heating precision of +/-1°C. It is particularly suited for drying delicate pharmaceuticals like lyophilized drugs, chemotherapeutic agents, and hormone drugs, where sensitive handling is paramount.
This vacuum tray dryer is applicable across various environments, from clean rooms to containment isolators, and supports batch operations while allowing for manual product loading and unloading. Its capacity ranges with model configurations, offering scalable solutions from 0.18 to 13.0 m² of usable shelf area.
Engineered for cGMP compliance, the system boasts easy-to-clean metallic surfaces, strategically designed to minimize product traps. PSL’s automation platform supports pre-designed process recipes, enhancing flexibility and speed in production, with compliance to GAMP5 and 21 CFR Part 11 standards, ensuring robust data recording and electronic signature protocols.
Additionally, the CakeStand™ can integrate seamlessly into existing containment setups, whether as stand-alone equipment or wall-integrated within isolators, optimizing space and adhering to safety standards for handling potent APIs and HPAPIs. Its design consideration for operator ease and effective containment measures underlines PSL’s commitment to combining performance with safety.
Benefits
- Ensures consistent product quality with precise temperature control across shelves.
- Enhances operational safety by integrating with containment systems for handling potent materials.
- Reduces cleaning time with easy-to-clean surfaces and minimized product traps.
- Increases production flexibility through pre-designed and customizable process recipes.
- Complies with stringent industry standards, supporting smooth audits and regulatory approvals.
- Applications
- Active pharmaceutical ingredients (api),Highly potent active pharmaceutical ingredients (hpapi),Fine chemicals,Pharmaceuticals
- End products
- Custom specialty chemicals,Controlled-release pharmaceuticals,Antivirals,Lyophilized drugs,Antibiotics,Peptide compounds,Enzyme preparations,Chemotherapeutic agents,Laboratory reagents,Cytostatics,Inhalable medications,Hormone drugs,Vaccine components
- Steps before
- Filtration,Transfer to Tray
- Steps after
- Loading and Unloading,Containment Handling,Packing
- Input ingredients
- delicate products,fragile products,pharmaceutical ingredients,API,HPAPI,product trays
- Output ingredients
- dried delicate products,dried fragile products,dried pharmaceutical ingredients
- Market info
- PSL (Powder Systems Limited) is known for designing and manufacturing advanced containment and process solutions for the pharmaceutical, biopharmaceutical, and chemical industries. They specialize in high-quality filtration, drying, and high containment systems.
- Heating uniformity
- ±1°C across shelves
- Chamber Volume
- 85 L to 2150 L
- Shelf Usable Area
- 0.18 to 13.0 m²
- Shelf Configurations
- 6 to 12 shelves
- Compliance
- cGMP designed
- Automation
- PSL Automation Platform
- Data Recording
- Software and Automation package
- Integration
- Available with downflow booths or isolators
- Working mechanism
- Vacuum chamber with direct heating shelves
- Batch vs. continuous operation
- Batch
- Integrated steps
- Loading,drying,unloading
- Compatible with containment measures
- Automation level
- PLC/SCADA compatible
- CIP/SIP
- cGMP cleaning-validation design
- Energy efficiency
- Uniform heating of +/-1°C across shelves
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine Footprint
- Subject to specific model size
- Chamber Volume
- 85 L - 2150 L
- Usable Shelf Area
- 0.18 m² - 13.0 m²
- Shelf and Tray Configurations
- 3 – 12 shelves
- Integration Options
- Downflow Booth / PSL GloveBox
- Shelf Type
- Direct Heating Shelves
- Door Type
- Front Flat Metallic Door
- Utility Connection Points
- Through-wall configuration
- Shelf Heating Accuracy
- ±1°C
- Suspended Shelves
- To avoid product traps
- Material of Construction
- All metallic internal parts
- Surface Finish
- Controlled for easy cleaning
- Edge and Corner Radiuses
- Designed for easy cleaning
- Control panel type
- PSL Automation Platform