Compact wet granulation r&d system

Ensure precise formulation of pharmaceutical powders with a scalable, lab-friendly system designed to seamlessly integrate sifting, mixing, drying, milling, and blending processes, all in one compact unit.

Integrates and Scales Pharmaceutical Batch Processes

The SigmaWall from SSPM Systems & Engineers Pvt. Ltd. is a versatile wet granulation system designed for seamless R&D to production-scale transitions in the pharmaceutical and biotech industries. Distinguished by its compact, plug-and-play design, it integrates key processes like sifting, mixing, drying, milling, and blending into a single system, optimizing space and reducing setup complexity.

The SigmaWall is particularly advantageous for developing sensitive products such as hormonal and oncology tablets, leveraging isolator compatibility to minimize cross-contamination risks. With capacities suited for various stages—from R&D batches to pilot-scale operations—it adapts easily to a range of production demands. Automation is facilitated through a PLC-controlled interface with CFR Part 11 compliance, ensuring data integrity and streamlined user management.

Material handling benefits from inbuilt systems that support safe and efficient transfer, while the option to include a tablet coating system enhances its versatility for full-spectrum product development. Its construction from GMP-compliant materials ensures robust performance and hygiene, with maintenance simplified by a tool-free design and remote IoT-based monitoring. Custom configurations are available, ensuring the equipment meets specific scale and compliance requirements.

Benefits

  • Enhances product safety by reducing cross-contamination with isolator compatibility.
  • Lowers maintenance costs with a tool-free, modular design.
  • Simplifies data management and regulatory compliance through CFR Part 11 compliance.
  • Increases operational efficiency by integrating multiple processes in one compact unit.
  • Facilitates scalability from R&D to production-scale seamlessly.

General


Applications
Oncology products,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Hormonal products
End products
Pharmaceutical-grade powder formulations,Cancer treatment tablets,Nutraceutical capsules,Birth control pills,Extended-release tablets,Protein powder supplements,Hormone replacement therapy tablets,Immediate-release tablets
Steps before
Purification,Weighing,Blending,Sifting
Steps after
Tablet Pressing,Coating,Batch Printing,Packaging
Input ingredients
batch materials,raw powders,granulation ingredients,hormonal products,oncology products
Output ingredients
granulated product,blended product,dried powders,milled particles,coated tablets
Market info

Technical Specifications


Sifter Capacity
12"
Rapid Mixer Granulator Capacity
2.5/5/7.5/10 Ltrs
Fluid Bed Dryer/Processor Capacity
2/5 Kg
Lab Co-Mill Capacity
20 to 40 Kg
Lab Blender Capacity
5/10/15/20/25 Ltrs
Tablet Coating
6"/12"/18"
Automation
Controlled through PLC and colour touch-screen HMI
Compliance
cGMP,21 CFR PART 11
Data Integrity
Retention of data and copies of records
Batch Printing Facilities
Available
Remote Service
IOT-based technology
Model
cGMP Model
Tool-Free Design
Lesser maintenance and tool-free

Operating Characteristics


Automation level
PLC / Manual
Batch vs. continuous operation
Batch
ISOLATOR COMPATIBILITY
OEL 3,OEL 4
Cleaning method
CIP
Energy efficiency
Low consumption
Changeover time
Minimal due to plug-and-play design
User control system
Common PLC and colour touch-screen HMI
Remote service capability
IOT-based technology

Material Compatibility


Cleanability
Designed with CIP / tool-free design
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Siftability
Yes
Mixability
High

Physical Characteristics


Compact footprint
Scalable,compact design
Control panel type
Colour touch-screen HMI
Machine footprint
Designed for small-scale R,D
Discharge method
Interchangeability of bowls and bins
Tablet coating integration
Inbuilt system

Custom Options


Control panel type
Common PLC and colour touch-screen HMI
Integration possibilities
Material transfer system,tablet coating system
Scalability
R,D to Pilot to Production-scale
Tool-free design
Yes
Footprint
Compact
User interface
User-friendly control system
Remote service capability
IOT-based technology