Compact wet granulation r&d system
Ensure precise formulation of pharmaceutical powders with a scalable, lab-friendly system designed to seamlessly integrate sifting, mixing, drying, milling, and blending processes, all in one compact unit.

Integrates and Scales Pharmaceutical Batch Processes
The SigmaWall from SSPM Systems & Engineers Pvt. Ltd. is a versatile wet granulation system designed for seamless R&D to production-scale transitions in the pharmaceutical and biotech industries. Distinguished by its compact, plug-and-play design, it integrates key processes like sifting, mixing, drying, milling, and blending into a single system, optimizing space and reducing setup complexity.
The SigmaWall is particularly advantageous for developing sensitive products such as hormonal and oncology tablets, leveraging isolator compatibility to minimize cross-contamination risks. With capacities suited for various stages—from R&D batches to pilot-scale operations—it adapts easily to a range of production demands. Automation is facilitated through a PLC-controlled interface with CFR Part 11 compliance, ensuring data integrity and streamlined user management.
Material handling benefits from inbuilt systems that support safe and efficient transfer, while the option to include a tablet coating system enhances its versatility for full-spectrum product development. Its construction from GMP-compliant materials ensures robust performance and hygiene, with maintenance simplified by a tool-free design and remote IoT-based monitoring. Custom configurations are available, ensuring the equipment meets specific scale and compliance requirements.
Benefits
- Enhances product safety by reducing cross-contamination with isolator compatibility.
- Lowers maintenance costs with a tool-free, modular design.
- Simplifies data management and regulatory compliance through CFR Part 11 compliance.
- Increases operational efficiency by integrating multiple processes in one compact unit.
- Facilitates scalability from R&D to production-scale seamlessly.
- Applications
- Oncology products,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Hormonal products
- End products
- Pharmaceutical-grade powder formulations,Cancer treatment tablets,Nutraceutical capsules,Birth control pills,Extended-release tablets,Protein powder supplements,Hormone replacement therapy tablets,Immediate-release tablets
- Steps before
- Purification,Weighing,Blending,Sifting
- Steps after
- Tablet Pressing,Coating,Batch Printing,Packaging
- Input ingredients
- batch materials,raw powders,granulation ingredients,hormonal products,oncology products
- Output ingredients
- granulated product,blended product,dried powders,milled particles,coated tablets
- Market info
- Sifter Capacity
- 12"
- Rapid Mixer Granulator Capacity
- 2.5/5/7.5/10 Ltrs
- Fluid Bed Dryer/Processor Capacity
- 2/5 Kg
- Lab Co-Mill Capacity
- 20 to 40 Kg
- Lab Blender Capacity
- 5/10/15/20/25 Ltrs
- Tablet Coating
- 6"/12"/18"
- Automation
- Controlled through PLC and colour touch-screen HMI
- Compliance
- cGMP,21 CFR PART 11
- Data Integrity
- Retention of data and copies of records
- Batch Printing Facilities
- Available
- Remote Service
- IOT-based technology
- Model
- cGMP Model
- Tool-Free Design
- Lesser maintenance and tool-free
- Automation level
- PLC / Manual
- Batch vs. continuous operation
- Batch
- ISOLATOR COMPATIBILITY
- OEL 3,OEL 4
- Cleaning method
- CIP
- Energy efficiency
- Low consumption
- Changeover time
- Minimal due to plug-and-play design
- User control system
- Common PLC and colour touch-screen HMI
- Remote service capability
- IOT-based technology
- Cleanability
- Designed with CIP / tool-free design
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Siftability
- Yes
- Mixability
- High
- Compact footprint
- Scalable,compact design
- Control panel type
- Colour touch-screen HMI
- Machine footprint
- Designed for small-scale R,D
- Discharge method
- Interchangeability of bowls and bins
- Tablet coating integration
- Inbuilt system
- Control panel type
- Common PLC and colour touch-screen HMI
- Integration possibilities
- Material transfer system,tablet coating system
- Scalability
- R,D to Pilot to Production-scale
- Tool-free design
- Yes
- Footprint
- Compact
- User interface
- User-friendly control system
- Remote service capability
- IOT-based technology