Stainless steel bioreactor for small-scale bioprocess production
Scaling up from lab-scale bioreactors to small-scale production requires a solution that ensures consistent and efficient transfer of processes. Without such technology, delays in production can result from challenges in customization and validation.
Streamline upstream bioprocessing
The Applikon BioPilot from Getinge is a pilot plant stainless steel bioreactor designed for upstream bioprocessing. This bioreactor is modular, using standard modules to facilitate customization for both microbial and cell cultures. It features a Sterilize-in-Place (SIP) system and a compact design that saves floor space. The bioreactor is constructed from pharma-grade 316L stainless steel with a surface finish of Ra < 0.4 micron, ensuring ease of cleaning and reducing contamination risks. The Applikon BioPilot's magnetically coupled agitator and consistent component scaling from lab-scale simplify validation and minimize human error. It complies with cGMP and GAMP standards, further easing the process of validation. This bioreactor is ideal for various applications, including scale-up studies and process optimization. The available volume capacities range from 30 liters to 270 liters, with options for microbial or cell culture operations.
Benefits
- Ease of customization with modular design
- Enhanced contamination control with SIP system
- Efficient cleaning with smooth internal surfaces
- Streamlined validation meeting cGMP and GAMP standards
- Suitable for both microbial and cell culture processes