Vertical centrifuge for plasma fractionation
Achieve high-purity plasma derivatives with precision; this vertical centrifuge ensures optimal yield and gentle treatment during plasma fractionation, vital for high-standard biopharmaceutical production.

Separates and Purifies Plasma Fractions Efficiently
The Series V 630 TS and V 800 TS from HEINKEL Drying and Separation Group are vertical centrifuges designed specifically for pharmaceutical applications, particularly in the separation of plasma fractions. These centrifuges effectively optimize the yield and purity of critical components such as albumin and immunoglobulins, thanks to their sophisticated design and operation. Utilizing a high-speed centrifugal force, they ensure efficient separation while maintaining the integrity of sensitive biological products.
These models are engineered to process multiple plasma derivatives, including clotting factors and immunoglobulins, commonly used in biopharmaceutical and fine chemical industries. With a processing framework that includes cooling, filling, centrifuging, discharging, and cleaning, they deliver a seamless integration into existing production lines. The double-walled housing ensures constant product temperatures, meeting GMP’s highest requirements and facilitating an environment for sterile operation.
The centrifuges feature a permanent direct drive system, enhancing performance dynamics with low space requirements due to their compact design. Moreover, automation is achieved through PLC-controlled operations which offer remote monitoring. The stainless steel construction supports excellent corrosion resistance, ensuring longevity and compatibility with various process environments. Cleaning is expedited via a CIP system, guaranteeing swift and contamination-free maintenance between batches. Designed with pharmaceutical manufacturers in mind, the Series V 630 TS and V 800 TS offer customizable throughput and rotor speeds to accommodate specific production needs.
Benefits
- Achieves high-purity plasma fractionation, enhancing product quality and yield.
- Reduces operational space with compact design, optimizing plant floor layout.
- Ensures sterile processing and compliance with GMP standards for safety and reliability.
- Minimizes contamination risk with efficient CIP cleaning system.
- Improves process efficiency with constant temperature control, maintaining product integrity.
- Applications
- Biopharmaceuticals,Fine chemicals,Plasma fractions,Pharmaceuticals
- End products
- Plasminogen,Coagulation factor viii,Intravenous immunoglobulins (ivig),Immunoglobulins (igg),Antithrombin iii,Coagulation factor ix,High-purity plasma derivatives,Albumin,Alpha-1 antitrypsin,Clotting factors,Human serum albumin
- Steps before
- Cooling,Filling
- Steps after
- Discharge of product,Cleaning
- Input ingredients
- blood plasma
- Output ingredients
- plasma fractions,valuable raw material,medicine substances
- Market info
- Heinkel is known for manufacturing high-quality industrial equipment, specializing in centrifuges, dryers, and other engineered-to-order machinery for the chemical, pharmaceutical, and environmental sectors, with a reputation for innovation and reliability.
- Basket diameter
- 630 mm / 800 mm
- Basket depth
- 315 mm / 420 mm
- Filter area
- 0.625 m² / 1.06 m²
- Nominal volume
- 250 L / 600 L
- Max. Filling
- 62 kg / 125 kg
- Max. Speed
- 3,000 1/min
- Centrifugal force
- 3,170 x g / 2,590 x g
- Temperature control
- Constant product temperature
- Sterile design
- Includes feed and suction pipe
- CIP cleaning
- Meets GMPC requirements
- Direct drive
- Permanent for higher dynamics and performance
- Compact design
- Low space requirement
- Cooling
- Included as part of the process
- Working Mechanism
- Plasma Fractionation
- Integrated Steps
- Cooling,Filling,Centrifugation,Discharge,Cleaning
- CIP Principles
- Sterile machine design according to GMP
- Batch vs. Continuous Operation
- Batch
- Automation Level
- Permanent direct drive
- Cleaning Method
- CIP
- Space Requirement
- Compact Design
- Temperature Control
- Double-walled Centrifuge Housing
- Biological compatibility
- Yes
- Cleanability
- CIP compliant
- Corrosive resistance (e.g. acids)
- Yes
- Abrasion resistance
- Yes
- Density/particle size
- 0.5–2.5 g/cm³ / Customizable size
- Machine footprint
- Compact design
- Basket diameter
- 630 mm / 800 mm
- Basket depth
- 315 mm / 420 mm
- Nominal volume
- 50 L / 100 L
- Max. Filling
- 62 kg / 125 kg
- Discharge method
- Top discharge
- Control panel type
- Permanent direct drive
- Centrifugal force
- 3,170 x g / 3,000 x g
- Dimensions
- Length
- Width
- 1,100 mm - 1,300 mm
- Height
- 1,680 mm - 2,060 mm
- Weight
- 2,200 kg / 3,200 kg
- Sterile machine design
- Includes feed pipe and suction pipe
- CIP cleaning
- Meets GMP requirements
- Clean room solution
- Yes
- Control panel type
- HMI / PLC
- Cooling system
- Double-walled centrifuge housing
- Compact footprint
- Low space requirement
- Sterile design
- Sterile feed pipe and suction pipe
- CIP cleaning
- Meets GMPC requirements