Bioprocessing liquid cell culture media
Streamline your bioprocessing with sterile liquid media solutions that ensure optimal production efficiency, from media and buffer preparation to final packaging, reducing contamination risks and freeing up resources for value-added activities.
Handles and Sterilizes Liquid Media and Buffers
This Bioprocessing Liquid Cell Culture Media and Buffer System supports pharmaceutical and biopharmaceutical manufacturers in enhancing production efficiency. It ensures precise handling and sterilization of liquid media, transforming complex processes like mAbs and mRNA development. Capable of integrating seamlessly into existing production lines, it employs sterile filtered systems to minimize contamination risks—ideal for fast-paced environments from bench to full-scale operations.
Processing capacity ranges from small to large-scale batches, accommodating diverse operational needs. Leveraging advanced single-use assembly systems, it reduces setup time and operational complexity. The system is compliant with ISO 9001:2015 and GMP standards, ensuring adherence to stringent regulatory requirements.
Energy efficiency is a core design feature, with a focus on sustainable operations through reduced water for injection usage and streamlined buffer preparation. It’s equipped with customizable options, including various material finishes to meet specific chemical compatibility needs. Maintenance is simplified by an integrated cleaning-in-place (CIP) system, which promotes rapid, contamination-free transitions between production cycles. This system stands out for its automation capabilities, with PLC control and remote monitoring to optimize workflow and ensure reliability in diverse bioprocessing applications.
Benefits
- Enhances production efficiency by minimizing contamination risks with sterile filtration.
- Streamlines workflow using customizable single-use assemblies, reducing operational complexity.
- Supports regulatory compliance with ISO 9001:2015 and GMP standards.
- Reduces water and resource use to promote sustainable operations.
- Facilitates fast, contamination-free transitions with an integrated CIP system.
- Applications
- Biologics,Biotechnology,Mabs development,Pharma manufacturing,Protein biology,Pharmaceutical processing,Drug filtration,Cell culture media,Biopharmaceuticals,Mrna development,Bioprocessing
- End products
- Biologic drugs,Downstream processing buffers,Sterile filtered drug solutions,Monoclonal antibodies,Biopharmaceutical production batches,Mrna vaccines,Cell culture media solutions,Protein therapeutics,Upstream fermentation media
- Steps before
- Media preparation,Buffer preparation,Cell culture,Cell suspension,Reconstitution of products
- Steps after
- Downstream processing,Diafiltration,Purification,Packaging,Quality control testing
- Input ingredients
- water for injection (WFI),bulk powders,cell culture media,buffers,media,in-process intermediates
- Output ingredients
- sterile filtered liquid media,sterile filtered buffers,final bulk drug product,cleaning and rinsing agents,diafiltration and purification buffers
- Market info
- Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.
- Compliance
- ISO 9001
- Product Type
- Sterile filtered liquid media and buffers
- Volume Capacity
- 100,200,500,or 1,000 liters
- Connector Type
- Sterile or non-aseptic connectors
- Packaging Options
- PET bottles,custom bags,single-use packaging
- Water Type
- Water for Injection (WFI)
- Use Case
- Upstream and downstream applications
- Delivery Method
- Ready-to-use
- Filtration
- Sterile filtered
- Sustainability
- Recyclable and reusable bulk liquid containers
- Sterile filtration capability
- ISO 9001
- Ready-to-use media and buffers
- Sterile filtered liquid
- Packaging options
- Mobius® single-use bags
- Batch vs. continuous operation
- Batch and Inline
- Automation level
- Customizable single-use packaging
- Changeover time
- Reduced with ready-to-use solutions
- Energy efficiency
- Streamlined processes to reduce energy use
- CIP/SIP
- Compatible with CIP principles
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Available container options
- Standard PET bottles,custom bags,custom volumes
- Volume format
- Custom volumes and formats
- Packaging options
- Standard or custom bags,single-use bags
- Delivery options
- Right-sized buffer delivery
- Mobius®MyWay Portfolio
- Customizable single-use assembly
- Connector type
- Sterile or non-aseptic connectors
- Transportation systems
- 3D large liquid transportation systems