Microsphere refiner for aseptic drug manufacturing
In pharmaceutical production, processing polymeric microspheres can be challenging, especially as batch sizes increase. Issues such as inconsistent product recovery, manual handling errors, and scaling difficulties often arise, necessitating an efficient, automated solution for seamless microsphere drug development and manufacturing.
Automate aseptic processing with high batch reproducibility
The MSR™ MicroSphere Refiner from Powder Systems Limited (PSL) is designed to address these challenges by offering a cGMP-compliant solution for a wide range of aseptic microsphere processes. It is capable of microsphere classification, filtration, de-watering, washing, drying (including freeze-drying), sampling, and discharge in one system. The fully automated system reduces manual intervention, thus minimizing the risk of human error and enhancing batch reproducibility. Process Analytical Technology (PAT) integration ensures real-time monitoring and quality control, aligning with FDA guidelines. With its flexible design, the MSR™ refiner maximizes product yield and allows easy scaling from R&D through to commercial production. It supports diverse vessel sizes and includes options for vacuum drying and freeze-drying.
Benefits
- Reduces the risk of human error with full automation
- Ensures consistent product quality with real-time PAT monitoring
- Maximizes product yield by minimizing transfers and connections
- Facilitates easy scaling from R&D to commercial production
- Supports multiple microsphere processes in one system