Single-use fermenter for microbial applications
Optimize biopharmaceutical production with a single-use fermenter engineered for efficient fermentation and high-growth microbial cultivation, enabling quick process transfer and enhanced automation in your operations.

Facilitates High-Density Microbial Fermentation
The Biostat STR® Microbial from Sartorius is a versatile single-use fermenter engineered for high-density microbial cultivation, particularly in biopharmaceutical applications such as pharmaceuticals, vaccines, and recombinant proteins. It combines the advantages of single-use technology with the robust performance of stainless-steel systems. The system leverages the Biobrain® automation platform, offering precise control over cultivation parameters for seamless process integration and scalability. Supporting working volumes up to 40 liters, it’s ideal for producing monoclonal antibodies, mRNA vaccines, and plasmid DNA. The Biostat STR® Microbial’s modular design allows easy process transfer, reducing operator risk and contamination through its single-use Flexsafe® STR bags. This system meets GMP standards, ensuring compliance and facilitating efficient waste disposal and maintenance with faster batch turnover due to minimized cleaning protocols. Customize and integrate effortlessly into existing operations with support for either cell culture or microbial processes, enhancing productivity and throughput in your production line.
Benefits
- Enhances productivity with quick batch turnover using single-use design.
- Ensures compliance and safety with GMP-ready system.
- Reduces contamination risk through disposable Flexsafe® STR bags.
- Integrates seamlessly into existing operations with modular setup.
- Minimizes operational costs by reducing cleaning and maintenance requirements.
- Applications
- Vaccines,Biopharmaceuticals,Fabs,Plasmid dna,Recombinant proteins
- End products
- Human insulin,Monoclonal antibodies,Mrna vaccines,Antibody fragments,Hepatitis b vaccine,Plasmid dna vaccines
- Steps before
- Sample Preparation,Media Preparation,Inoculation,E. coli Cultivation Setup
- Steps after
- Waste Disposal,Sterile Filtration,Product Harvesting,Downstream Processing,Purification
- Input ingredients
- microbial cultures,E. coli,cell culture media,buffers,reagents,growth factors,plasmid DNA,recombinant proteins,flexsafe STR bags,single-use assemblies
- Output ingredients
- plasmid DNA,recombinant proteins,vaccines,fAbs,high cell density cultures,waste disposal
- Market info
- Sartorius AG is renowned for manufacturing high-precision laboratory and bioprocess equipment. They specialize in filtration, fermentation, and cell cultivation systems, known for their innovation and reliability in the pharmaceutical and biotech industries.
- Working Volume
- Up to 40 L
- Optical Density (OD600)
- > 300
- Mass Transfer Coefficient (kLa)
- 675 1/h
- Stirring Speed
- 500 rpm
- Gas Flow Rate
- 1.5 vvm
- Specific Growth Rate
- 0.15 h-1
- Cooling Efficiency
- Efficient
- Automation Platform
- Biobrain®
- Batch Turnover Time
- Fast
- Batch vs. continuous operation
- Batch
- Automation level
- PLC / SCADA
- Changeover time
- Fast batch-to-batch turnover
- CIP/SIP
- Single-use design,negates CIP
- Cleaning method
- Single-use bags,no extensive cleaning required
- Energy efficiency
- High productivity,efficient cooling and gas flow
- Process control
- GMP-ready system with Biobrain® automation
- Process transfer
- Seamless conversion from stainless steel processes
- Setup time
- Faster setup with modular design
- Biological compatibility
- Supports plasmid DNA,fAbs,recombinant proteins,vaccines
- Corrosive resistance (e.g. acids)
- Designed for microbial applications
- Cleanability
- Single-use Flexsafe STR® bags negate extensive cleaning protocols
- Abrasion resistance
- Combines single-use with stainless-steel performance
- Batch turnover time
- Fast batch-to-batch turnover
- Working volume
- Up to 40 L
- System type
- Single-use
- Bag type
- Flexsafe STR bags
- Control panel type
- Biobrain® automation platform
- Modular Design
- Accommodates cell culture or microbial bag holders
- Integration possibilities
- Integrates with DCS for process control
- Compact footprint
- Space-saving design