Bioreactor mixer for gentle mixing applications
When handling sensitive biomaterials, ensuring optimal mixing while maintaining sterility and minimizing mechanical stress is critical. This bioreactor mixer excels in gentle mixing, safeguarding the integrity of delicate compounds in your bioprocess.
Facilitates Gentle Aseptic Mixing in Bioreactors
The Zero-g Biomixer from Metenova is a magnetically coupled, bottom-mounted mixer specifically designed for aseptic and sterile bioreactor applications. Its patented Zero Gravity Technology features a magnetic bearing system that minimizes wear, ensuring reliable operation and reduced maintenance. This technology creates a magnetic cushion, allowing for gentle, efficient mixing with minimal risk of damage to impellers, making it well-suited for producing high-purity biologics, including monoclonal antibodies and DNA/RNA vaccines. The mixer supports customization of impeller designs to meet specific process requirements, reducing the need for revalidation. By eliminating mechanical seals, it enhances aseptic integrity, and its robust design withstands higher forces associated with large bioreactor vessels. Additionally, it is engineered for quick integration and minimized downtime with a focus on CIP/SIP (Cleaning-In-Place/Sterilization-In-Place) for contamination-free cleaning, supporting compliance with stringent industry standards like GMP and FDA.
Benefits
- Ensures product integrity by maintaining strict aseptic conditions.
- Minimizes maintenance and increases uptime with durable magnetic bearings.
- Reduces the need for revalidation through customizable impeller designs.
- Enhances compatibility with large vessels due to heavy-duty construction.
- Complies with GMP and FDA standards for biopharmaceutical manufacturing.
- Applications
- Aseptic processes,Sterile vessels,Nutraceuticals,Biopharmaceuticals,Bioreactors
- End products
- Nutritional supplements,Monoclonal antibodies,Enzyme blends,Herbal extracts,Dna/rna vaccines,Recombinant proteins,Sterile injectable solutions,Infusion bags,Probiotics
- Steps before
- Customization,Mixing Preparation
- Steps after
- Cleaning,Sterilization
- Input ingredients
- biomaterials,liquids,cell cultures
- Output ingredients
- mixed biomaterials,homogeneous bioreactor contents
- Market info
- Mete Nova is known for its expertise in manufacturing customized engineered-to-order (ETO) industrial equipment, acclaimed for its precision engineering, reliability, and tailored solutions to meet specific client needs across various industrial sectors.
- Mounting type
- Bottom-mounted
- Mixing type
- Magnetically coupled
- Designed for
- Aseptic processes
- Mixing application
- Bioreactors
- Bearing technology
- Zero Gravity Technology
- Maintenance requirement
- Minimum
- Impeller customization
- Available
- Batch cleaning
- CIP/SIP
- Working Mechanism
- Magnetically coupled,bottom-mounted
- CIP/SIP
- Aseptic and sterile
- Batch vs. Continuous Operation
- Batch
- Installation
- Safe and robust
- Automation Level
- Not specified
- Maintenance Requirement
- Minimum
- Aseptic Design
- High level
- Integrity
- High,magnetically coupled
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Shear sensitivity
- Suitable for gentle and shear-sensitive applications
- Machine footprint
- Compact design
- Mounting type
- Bottom-mounted
- Impeller design
- Customizable bioreactor impellers
- Bearing design
- Zero Gravity Technology bearing
- Shaft design
- Long shafts with wider blades
- Installation ease
- Magnetic “cushion” for safe installation
- Structure
- Multistage bioreactor mixer
- Impeller design customization
- Bioreactor-specific impellers
- Magnetic coupling
- Zero Gravity Technology
- Heavy-duty bearing design
- Yes
- Bottom-mounted design
- Aseptic and robust