Lab-scale fermentors for microbial cultivation

Optimize microbial cultivation with lab-scale fermentors designed for precise control over fermentation processes, addressing challenges such as oxygen supply, temperature regulation, and automated dosing, ensuring high-quality yield consistency even in challenging environments.

Cultivates Microorganisms and Optimizes Fermentation Conditions

The stainless steel fermentor from Bioengineering is engineered to streamline microbial cultivation for the biopharmaceutical and nutraceutical industries. This equipment leverages advanced aeration strategies and precise control over oxygen supply, dosage, and temperature, ensuring optimal fermentation conditions for producing insulin, vaccines, and monoclonal antibodies. With capacities ranging from 30 to 50,000 liters, the fermentor accommodates both pilot and full-scale production. Designed for seamless integration into existing production lines, it features a PLC-controlled system for automated operations and offers compatibility with various control software, including BioSCADA, for intuitive management. Compliant with GMP standards, the fermentor includes integrated CIP systems for efficient cleaning and maintenance. Additionally, Bioengineering provides customization options to suit specific production needs, backed by over 50 years of industry expertise.

Benefits

  • Enhances production efficiency with precise control over fermentation parameters.
  • Reduces operational costs through automation and seamless integration with existing control systems.
  • Supports a wide range of applications, from pharmaceuticals to nutraceuticals, enabling diverse product output.
  • Ensures compliance with industry standards, promoting safe and high-quality manufacturing.
  • Minimizes contamination risk with integrated CIP systems for effective cleaning.

General


Applications
Food,Homeopathy,Metal powders,Liquid formulations,Fine chemicals,Snacks,Nutraceuticals,Beverage,Performance materials,Alternative medicine,Cosmetics,Biopharmaceuticals,Pharmaceutical products,Biofuel
End products
Metal alloy powders,Protein powders,Vaccines,Flavored beverages,Analgesic tablets,Nutritional snack bars,Insulin,Liquid cough syrups,Monoclonal antibodies,Vitamin supplements,Homeopathic tinctures,Biodiesel,Ceramic coatings,Essential oils
Steps before
Microbial Cultivation,Process Requirement Determination,Stainless Steel Fabrication,Design and Engineering,Oxygen Supply Optimization,Stirrer Dimensioning,Heating and Cooling Circuit Setup
Steps after
Sterilization,Aeration Strategy Development,Dosage Vessel Integration,Continuous Fermentation,GMP Production Compliance,High Cell Density Management
Input ingredients
bacteria,archaea,yeast,extremophiles,oxygen,corrective agents,acids,bases,anti-foams,culture media
Output ingredients
microbial cultivation,fermented cultures,microorganism,high cell density cultures
Market info
Bioengineering is known for its expertise in designing and manufacturing customized bioreactors and fermenters, serving the biotechnology and pharmaceutical industries. They are reputed for high-quality, engineered-to-order solutions and innovative process technologies.

Technical Specifications


Fermentor Capacity
30 to 50,000 liters
Vessel Geometry Ratio (h
d)
Oxygen Supply/Aeration
Customizable,High kLa
Heating/Cooling Circuit
Fast-Response
Automation
BioSCADA Software
Stirrer Dimensioning
Customizable
Material
Stainless Steel cGMP
Microorganisms Supported
Bacteria,Archaea,Yeast,Extremophiles
CIP/SIP Capability
Integrated
Temperature Control
Rapid Heating/Cooling
Dosage Vessels
For acids,bases,anti-foams

Operating Characteristics


Automation level
SCADA / PLC
Batch vs. continuous operation
Batch / Continuous
CIP/SIP capability
CIP / SIP
Short heating and cooling periods
Priority for culture media
Dosage integration
Acids,bases,anti-foams
Customized fermentation system
Based on microorganism requirements

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Microbial cultivation type
Bacteria,archaea,yeast,extremophiles

Physical Characteristics


Tank shape
Cylindrical
Tank size
30 to 50,000 liters
Typical vessel geometry
h
Machine footprint
N/A
Control panel type
Intuitive HMI

Custom Options


Control panel type
Intuitive HMI
Integration possibilities
BioSCADA software
Software architecture
Optimized for Bioreactor environment
Vessel capacity range
30 to 50,000 liters
Vessel geometry
h
Heating and cooling circuit options
Short heating and cooling periods
Aeration strategies
Customizable with high kLa value
Dosage system
Fully integrated dosage vessels
Material
Stainless steel (cGMP)