Pilot Gmp spray dryer system for small-scale manufacturing

For precise control in spray drying, streamline your small-scale manufacturing and clinical batch processes with closed-loop nitrogen systems that enhance solvent safety and recovery.

Processes and Dries with Solvent Recovery

The GSD-800 GENESIS™ from Freund is a GMP-compliant spray dryer highly suited for biopharmaceutical and chemical industries. It features a closed-loop system with nitrogen inerting for safely processing heat-sensitive materials while recovering solvents efficiently. This system accommodates a diverse range of applications, including the production of vitamins, enzymes, and pharmaceutical tablets. With an evaporation capacity of 4 kg/hr for water-based solutions, it ensures precise control over particle size and moisture content. The GSD-800 integrates seamlessly with your production line through its user-friendly COMPU™ control system, offering minimal operator interaction and optional 21 CFR Part 11 compliance for data integrity. Its modular gas disperser and various nozzle options allow tailored adjustment to meet specific particle characteristics and drying requirements. Built from durable materials that ensure chemical resistance, the system also includes an innovative cleaning mechanism for straightforward maintenance and removal of all product contact surfaces.

Benefits

  • Enhances production efficiency with closed-loop nitrogen inert processing, ensuring safe and controlled drying environments.
  • Optimizes resource use through solvent recovery, reducing waste and operational costs.
  • Facilitates production transitions with easy-to-clean design, minimizing downtime during maintenance.
  • Supports regulatory compliance with GMP-compliant design and optional 21 CFR Part 11 data handling.
  • Offers versatile application customization through adjustable cyclone configurations and nozzle selections for precise particle management.

General


Applications
Supplements,Vitamins,Liquid formulations,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals,Enzymes,Coating materials
End products
Biologics,Ibuprofen tablets,Enteric coatings,Pharmaceutical grade lactose,Coenzyme q10 capsules,Fish oil softgels,Lipase enzyme powder,Vitamin d3 microencapsulation,Ascorbic acid tablets,Liquid cough syrup formulations
Steps before
Fluid Bed Granulation,Wet Granulation,Solution Preparation
Steps after
Powder Collection,Ingredient Mixing,Packaging
Input ingredients
water,solvents,small-scale manufacturing materials,clinical batch materials,slow drying small dense particles,heat sensitive substances
Output ingredients
dried particles,uniformly atomized droplets,powder collection,solvent recovery
Market info
Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.

Technical Specifications


Evaporation Capacity (Water)
4 kg/hr
Chamber Diameter
800 mm
Nozzle Type
2-Fluid (standard),Pressure (Optional),Rotary Atomizer (Optional),Twin Jet (Optional)
Drying Gas Flow Rate
120 kg/hr
Compressed Air Supply
13.6 m³/hr @ 6 bar
Nitrogen Supply
10.2 m³/hr @ 6 bar
Electrical Supply
230 – 575 VAC,50 – 60 Hz,3 Phase
Weight
1280 kg (approximate)
Design Standards
CE,ATEX,UL,NFPA,CSA
Solvent Rating
Class 1,Division 2 / ATEX Zone 2

Operating Characteristics


Automation level
Minimal operator interaction
Cleaning method
Total access cleaning
Batch vs. continuous operation
Batch and small-scale manufacturing
CIP/SIP
Tool-less hardware throughout
Energy efficiency
Tankless WIP skid for lower costs
Integrated steps
Closed loop spray drying
Working mechanism
Nozzle atomization
Changeover time
Easy disassembly
Residence time
Increase with drying chamber extensions

Material Compatibility


Cleanability
Full access for cleaning
Corrosive resistance
Suitable for solvent processing
Density/particle size
Configurable cyclone for particle attributes

Physical Characteristics


Machine Footprint
Compact design
Chamber Diameter
800mm
Discharge Method
Exhaust fines filter
Drying Chamber Extensions
Configurable
Control Panel Type
Color Touch Screen HMI

Custom Options


Control panel type
Color Touch Screen HMI
Gas Disperser
Modular with Exchangeable Components
Cyclone Configurations
Range of Exchangeable Sections and Inserts
Spray Devices
2-Fluid Nozzle,Pressure Nozzle,Rotary Atomizer,Twin Jet
Closed-Cycle Insert Gas Loop
Yes
Total Access Cleaning
Tool-less Hardware for Easy Access and Cleaning
Peristaltic Pump System
With Solution Tank (1 liter)