Pilot Gmp spray dryer system for small-scale manufacturing
For precise control in spray drying, streamline your small-scale manufacturing and clinical batch processes with closed-loop nitrogen systems that enhance solvent safety and recovery.

Processes and Dries with Solvent Recovery
The GSD-800 GENESIS™ from Freund is a GMP-compliant spray dryer highly suited for biopharmaceutical and chemical industries. It features a closed-loop system with nitrogen inerting for safely processing heat-sensitive materials while recovering solvents efficiently. This system accommodates a diverse range of applications, including the production of vitamins, enzymes, and pharmaceutical tablets. With an evaporation capacity of 4 kg/hr for water-based solutions, it ensures precise control over particle size and moisture content. The GSD-800 integrates seamlessly with your production line through its user-friendly COMPU™ control system, offering minimal operator interaction and optional 21 CFR Part 11 compliance for data integrity. Its modular gas disperser and various nozzle options allow tailored adjustment to meet specific particle characteristics and drying requirements. Built from durable materials that ensure chemical resistance, the system also includes an innovative cleaning mechanism for straightforward maintenance and removal of all product contact surfaces.
Benefits
- Enhances production efficiency with closed-loop nitrogen inert processing, ensuring safe and controlled drying environments.
- Optimizes resource use through solvent recovery, reducing waste and operational costs.
- Facilitates production transitions with easy-to-clean design, minimizing downtime during maintenance.
- Supports regulatory compliance with GMP-compliant design and optional 21 CFR Part 11 data handling.
- Offers versatile application customization through adjustable cyclone configurations and nozzle selections for precise particle management.
- Applications
- Supplements,Vitamins,Liquid formulations,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals,Enzymes,Coating materials
- End products
- Biologics,Ibuprofen tablets,Enteric coatings,Pharmaceutical grade lactose,Coenzyme q10 capsules,Fish oil softgels,Lipase enzyme powder,Vitamin d3 microencapsulation,Ascorbic acid tablets,Liquid cough syrup formulations
- Steps before
- Fluid Bed Granulation,Wet Granulation,Solution Preparation
- Steps after
- Powder Collection,Ingredient Mixing,Packaging
- Input ingredients
- water,solvents,small-scale manufacturing materials,clinical batch materials,slow drying small dense particles,heat sensitive substances
- Output ingredients
- dried particles,uniformly atomized droplets,powder collection,solvent recovery
- Market info
- Freund is known for its expertise in granulation and coating technology, supplying high-quality industrial equipment for pharmaceutical, chemical, and food industries. Renowned for innovation and reliability, Freund consistently delivers engineered-to-order solutions tailored to client needs.
- Evaporation Capacity (Water)
- 4 kg/hr
- Chamber Diameter
- 800 mm
- Nozzle Type
- 2-Fluid (standard),Pressure (Optional),Rotary Atomizer (Optional),Twin Jet (Optional)
- Drying Gas Flow Rate
- 120 kg/hr
- Compressed Air Supply
- 13.6 m³/hr @ 6 bar
- Nitrogen Supply
- 10.2 m³/hr @ 6 bar
- Electrical Supply
- 230 – 575 VAC,50 – 60 Hz,3 Phase
- Weight
- 1280 kg (approximate)
- Design Standards
- CE,ATEX,UL,NFPA,CSA
- Solvent Rating
- Class 1,Division 2 / ATEX Zone 2
- Automation level
- Minimal operator interaction
- Cleaning method
- Total access cleaning
- Batch vs. continuous operation
- Batch and small-scale manufacturing
- CIP/SIP
- Tool-less hardware throughout
- Energy efficiency
- Tankless WIP skid for lower costs
- Integrated steps
- Closed loop spray drying
- Working mechanism
- Nozzle atomization
- Changeover time
- Easy disassembly
- Residence time
- Increase with drying chamber extensions
- Cleanability
- Full access for cleaning
- Corrosive resistance
- Suitable for solvent processing
- Density/particle size
- Configurable cyclone for particle attributes
- Machine Footprint
- Compact design
- Chamber Diameter
- 800mm
- Discharge Method
- Exhaust fines filter
- Drying Chamber Extensions
- Configurable
- Control Panel Type
- Color Touch Screen HMI
- Control panel type
- Color Touch Screen HMI
- Gas Disperser
- Modular with Exchangeable Components
- Cyclone Configurations
- Range of Exchangeable Sections and Inserts
- Spray Devices
- 2-Fluid Nozzle,Pressure Nozzle,Rotary Atomizer,Twin Jet
- Closed-Cycle Insert Gas Loop
- Yes
- Total Access Cleaning
- Tool-less Hardware for Easy Access and Cleaning
- Peristaltic Pump System
- With Solution Tank (1 liter)