Continuous aseptic spray-freeze-drying system
Achieving consistent, high-quality freeze-dried products in pharmaceuticals often requires overcoming challenges such as sterility assurance and long drying times. Traditionally, freeze-drying processes involve multiple stages and extensive material handling, increasing the risk of contamination and downtime.
Delivers continuous and controlled freeze-drying
The Lynfinity by IMA is a continuous aseptic spray-freeze-drying system designed to streamline the freeze-drying process from bulk liquid to dried particles. It begins with a controlled spray of liquid product into a cryogenically cooled freezing chamber, creating frozen particles. These particles are then transferred to a drying module where they are heated to promote rapid sublimation, preventing agglomeration. The system ensures total containment from formulation to powder filling, which enhances sterility assurance levels significantly compared to traditional methods. Ideal for pharmaceutical applications, the Lynfinity reduces downtime and operational costs while providing greater throughput flexibility and improved product uniformity. Key highlights include minimized scale-up and scale-down challenges, reduced drying time, and no vapor flow limitations. The compact design also lowers both capital and operational expenditures.
Benefits
- Ensures higher sterility assurance levels
- Reduces operational and utility costs
- Minimizes scale-up and scale-down challenges
- Improves product uniformity with gentle drying
- Lowers equipment footprint and no loading system requirement