Fluid bed combo for top-spray granulation and wurster coating

Optimize your batch processing with a versatile system capable of granulation, drying, and coating, tailored for efficient handling of powders and granules in pharmaceutical and nutraceutical applications.

Processes Granulation, Drying, and Coating in One Unit

The FBE 250C, part of ACG’s fluid bed combo series, is designed to address your pharmaceutical and nutraceutical processing needs by combining granulation, drying, and coating processes into one efficient system. Its innovative integration of top-spray and Wurster coating technology enables versatile applications, including the production of tablets, capsules, and powders. With a working capacity of up to 250 liters per batch, it supports various production scales. The machine’s PLC-controlled operations ensure precise process adjustments and seamless integration into production lines. Featuring a state-of-the-art twin-chamber filter bag shaking system, it provides continuous fluidization and reduces compressed air consumption. Constructed with multiple air distribution options and available in corrosion-resistant materials, it meets the rigorous standards of GMP and FDA compliance. Customizable features, including charging, discharging, and wash-in-place systems, coupled with ACG’s engineering support, make it an adaptable choice for diverse manufacturing environments.

Benefits

  • Enhances process efficiency by integrating multiple operations, reducing total processing time.
  • Minimizes compressed air usage, lowering operational costs and energy consumption.
  • Ensures safety with a precisely calculated vent system for pressure shock containment.
  • Adaptable to various product needs with multiple air distribution configurations.
  • Simplifies maintenance and cleaning through customizable wash-in-place systems.

General


Applications
Nutraceuticals,Vitamins,Supplements,Pharmaceuticals
End products
Mineral supplements,Pharmaceutical tablets,Nutraceutical capsules,Vitamin tablets,Probiotic capsules,Protein powder blends,Herbal extracts,Dietary supplements
Steps before
Purification,Emulsification,Grinding
Steps after
Coating,Tablet Pressing,Packing
Input ingredients
raw materials,pharmaceutical excipients,active pharmaceutical ingredients,nutraceutical ingredients
Output ingredients
granulated formulations,coated particles,dry powders,layered drug formulations
Market info
ACG World is known for manufacturing capsules and capsule filling machines, providing integrated pharmaceutical solutions with a strong reputation for innovation, quality, and comprehensive service offerings in the pharmaceutical manufacturing industry.

Technical Specifications


Batch size
70–344 l
Top-spray granulation
70 l Min,344 l Max
Wurster coating
23 l Min,170 l Max
Automation
PLC-controlled
Compressed Air Usage
Far less than blowback filter systems
Air distribution plates
Multiple

Operating Characteristics


Working Mechanism
Fluidized Bed
Integrated Steps
Drying,Granulation,Coating
CIP/SIP
Customised wash-in-place (WIP)
Batch vs Continuous Operation
Batch
Cleaning Method
Customised CIP
Automation Level
PLC Controlled
Air Incorporation Control
Twin-chamber filter bag shaking system

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Maximum batch size
250 L
Design type
Combo with top-spray and Wurster coating
Discharge method
Customised discharging system
Vent system
Precisely calculated and tested
Filter system
Twin-chamber filter bag shaking system

Custom Options


Air distribution selection
Multiple air-distribution plates
Charging and discharging configuration
Customised systems available
Wash-in-place (WIP) system
Standalone and granulation-train configurations
Coating technology
Top-spray and Wurster coating